Basic Information
English translation: AkUrsole® Bearberry Acid
English name: AkUrsole® Ursolic acid
INCI name: URSOLIC ACID
CAS Number: 77-52-1
Molecular formula: C30H48O3
Molecular weight: 456.7 g/mol
Specification: 90% – 98% minimum
Detection method: HPLC
Properties: White powder
Packaging specification: 25kg per barrel or as per customer’s requirements
Storage conditions: Store in a cool and dry place, avoiding direct sunlight and high temperatures.
Mechanism of action
Remove free radicals
In the meta-analysis of the antioxidant activity of arbutin, by combining the data from animal and in vitro experiments, it was shown that arbutin could significantly increase the levels of antioxidant indicators such as SOD and GSH, and reduce the contents of oxidative stress markers such as MDA. 1
Affect the production of pro-inflammatory cytokines
In the study of the atopic dermatitis mouse model induced by DNCB, through ELISA detection, it was shown that ericetin could down-regulate the levels of pro-inflammatory factors such as IL-1β, IL-6 and TNF-α in the lesion tissues, and its effect was related to the inhibition of the TLR4/NF-κB pathway. 2
Promote collagen production
In the study of the normal human dermal fibroblast cell model cultivated in vitro, through the treatment with liposomalursolic acid and the quantitative detection of collagen, it was shown that liposomalursolic acid could significantly promote the synthesis of collagen by fibroblasts and increase the collagen content within the cells. 3
Applications
Face cream and essence: In face creams and essence solutions, arbutin is often added as the main ingredient.
Lotion and Body Care: In products such as body lotion and hand cream, arbutin can be used as a skin conditioner and antioxidant.
Product advantages
Natural safety: The source material, loquat leaves, has a history of use for over a thousand years and is highly regarded for its safety.
Stable supply: With years of experience in the production of natural substances, we can ensure stable large-scale production.
Global Compliance: Certified to multiple national regulations, supporting compliance entry into international markets
Samples and further technical data can be provided upon request.
More details, just contact: Nicole@coreychem.com
