📋Basic Information and Safety Data
Chinese Common Name: Sweet Orange Flavonoid, Kudzu Glycoside, 3′,4′,5,6,7-Penta-methoxyflavone.
English name: Sinensetin.
Physical properties: Light yellow or white to beige powdery solid.
Solubility: Soluble in DMSO (up to 3 mg/mL, requires heating), generally insoluble in water.
Storage conditions: It is recommended to store at 2-8°C in the refrigerator and keep it sealed and protected from light.
Safety: Harmful if ingested. May cause skin, eye irritation and respiratory tract irritation. Protective equipment should be worn during operation. In case of accidental ingestion, seek medical attention immediately.
🌿Natural origin
This compound is not unique to artificial synthesis; rather, it is naturally present in a variety of plants, mainly including:
Fruits of the Rutaceae family belonging to the Citrus genus (such as citron, sweet orange)
Flora of the Labiatae family (such as Motherwort, Cat’s Tail Grass)
Leguminous plants (such as dragon vine)
Plants of the Rutaceae family belonging to the genus Syzygium (such as Syzygium lawrencei)
💊Main biological activities
Studies have shown that 5,6,7,3′,4′-pentamethoxyflavone has extensive pharmacological potential:
Anti-inflammatory and anti-proliferative: One of its most significant activities, it is used as an anti-inflammatory reagent for research purposes.
Anti-cancer potential: Molecular docking studies predict that it has potential anti-cancer activity, and the number of related targets accounts for the highest proportion in the prediction results.
Cardiovascular protection: Demonstrates vasodilatory activity and can inhibit platelet adhesion.
Other activities: include antioxidant, antimicrobial, anti-obesity and neuroprotective (anti-dementia) effects
🔬Research application
In laboratory research, it is often used as an analytical standard. Through methods such as high-performance liquid chromatography (HPLC), the content of this component in Chinese medicinal materials or natural product extracts can be qualitatively and quantitatively analyzed.
Lucy@coreychem.com
