I. Product information
| Product name:(R)-3-Ammonio-3-(4-(methylsulfonyl)phenyl)propanoate |
CAS:712321-07-8 |
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Appearance:white to off-white crystalline powder |
Purity:97% min |
|
MF：C10H13NO4S |
MW:243.28 |
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Transport Information: Non-dangerous goods |
HS Code:2914790090 |
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Packaging:1kg/5kg/25kg or According to customers’ requirements |
Storage:Store in a tightly sealed container in a cool, dry, and well-ventilated place. |
Product manager email: eva@coreychem.com
II. Product properties
| Chemical Properties: | As an amino acid derivative, it possesses the reactivity of both amino and carboxyl groups, enabling various reactions such as salt formation, condensation, and acylation. Its chiral structure is crucial for asymmetric synthesis and biological activity. |
| Solubility: | Generally soluble in polar organic solvents (e.g., DMSO, DMF), dilute acidic or basic aqueous solutions. Solubility in water may be limited. |
| Purity & Quality Control: | As a pharmaceutical intermediate, its chiral purity (enantiomeric excess, e.e.) is a critical quality parameter, typically requiring strict analysis by methods like chiral HPLC. |
III. Application
Core Application Areas:
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Neuraminidase Inhibitors: This compound serves as a key chiral building block for synthesizing certain potent and selective neuraminidase inhibitors. These inhibitors are used to treat influenza by preventing the spread of the virus within the body. The methylsulfonylphenyl moiety and the chiral amino acid side chain are essential for binding to the viral enzyme’s active site.
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Medicinal Chemistry Research: As a starting material or intermediate containing specific pharmacophores (methylsulfonyl, chiral β-amino acid), it is widely used in the design and synthesis of novel drug candidates, particularly in the fields of antiviral, anti-inflammatory, or neurological disease therapies.
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Bioconjugation & Probes: Its amino and carboxyl groups can be utilized to link other functional molecules, making it useful in chemical biology for preparing bioactive probes or targeted delivery systems.
