Contact Manager: Emma Song Email Address: emma@coreychem.com
|
Product Name: |
(R)-1-Boc-3-Aminopiperidine |
CAS NO: |
188111-79-7 |
|
Molecular Formula: |
C10H20N2O2 |
Molecular Weight: |
200.28 |
|
Items |
Specifications |
Test Result |
|
Appearance |
Colorless to light yellow liquid or solid |
Light yellow liquid |
|
Identification |
In the chromatogram recorded under assay testing, the retention time of the main peak of the test solution should be consistent with that of the reference solution. |
Conform |
|
Water |
≤0.5% |
0.17% |
|
Purity |
≥99.0% |
99.86% |
|
Any unspecified impurity |
≤0.2% |
0.03% |
|
Assay |
98.0%~102.0% |
100.5% |
|
Chiral purity |
≥99.5% |
>99.9% |
Uses: (R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.
R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.
General Description: (R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.
