Tris(2-pyridylmethyl)amine is an intermediates of synthetic materials and aggregation reagent.
Today, ATRP is one of the most powerful polymer synthetic methods which allows control over molecular architecture, as evidenced by over one hundred patent applications, over a thousand journal articles published annually.
Various metals and ligands have been successfully employed as catalystsin ATRP, but the most often used are the catalysts based on copper (thetwo oxidation states are CuI and CuII) and N-containing ligands. Onedrawback of the classical ATRP is the use of high amounts of thecatalyst,so the obtained polymersrequire tediouspurification to remove the catalyst.
However, the use of tris(2-pyridylmethyl)amine alleviatesthis problem. The ligand can be used in new techniquescalledInitiators for Continuous Activator Regeneration (ICAR)which allow todecrease amount of catalyst to only few, often single-digit, ppm. For comparison, 1,000 to 10,000 ppm were used in traditional ATRP.