Water-18O

Water-18O (CAS: 14314-42-2) is a stable isotope-labeled compound widely utilized in scientific research, pharmaceutical development, and advanced analytical applications. Featuring oxygen-18 as a non-radioactive isotopic tracer, it enables precise tracking of oxygen atoms in chemical and biological systems, making it an essential tool for complex mechanism studies and quantitative analysis. Its primary applications are outlined below:

1. Organic Synthesis & Pharmaceutical Research

Isotope Labeling & Mechanistic Studies

Water-18O is widely used to introduce oxygen-18 into target molecules, enabling detailed investigation of reaction mechanisms, oxygen exchange processes, and catalytic pathways in organic synthesis.

Drug Metabolism & Pharmacokinetics

In pharmaceutical research, it serves as a tracer for studying metabolic pathways, drug absorption, distribution, and excretion, supporting accurate evaluation of pharmacokinetic behavior and drug development.

2. Environmental & Geochemical Applications

Hydrological & Environmental Tracing

Water-18O is extensively applied in environmental studies to trace water sources, track hydrological cycles, and analyze climate-related processes such as evaporation and precipitation patterns.

Geochemical & Isotope Analysis

It is used in isotope ratio studies to investigate geological formations, paleoclimate conditions, and water–rock interactions, providing valuable data for earth science research.

3. Advanced Analytical & Scientific Research

Mass Spectrometry & Quantitative Analysis

As a high-purity isotopic standard, Water-18O is used in mass spectrometry and isotope ratio analysis to improve accuracy, sensitivity, and reproducibility in quantitative measurements.

Biochemical & Life Science Research

It is applied in enzymatic studies and biochemical pathway analysis to track oxygen incorporation in biological systems, supporting research in molecular biology and life sciences.

4. Research & Development Applications

Molecular Design & Process Investigation

Researchers utilize Water-18O to explore reaction kinetics, oxygen transfer mechanisms, and system dynamics, enabling optimization of chemical processes and experimental models.

Method Development & Calibration

Its well-defined isotopic composition makes it suitable as a reference material for calibration, validation of analytical methods, and development of new experimental techniques.

5. Handling & Storage

Storage Conditions

Store in tightly sealed containers under clean, dry conditions to avoid contamination and isotopic dilution.

Intended Use

Water-18O is intended for research, development, and industrial analytical applications. It is not for direct pharmaceutical or food use without appropriate regulatory approval.

Summary

The value of Water-18O lies in its role as a precise and reliable isotopic tracer. Its unique ability to track oxygen atoms enables advanced studies in chemical reactions, biological systems, and environmental processes, supporting innovation in pharmaceutical research, analytical science, and geochemical investigation.