Home » Products » Pharmaceuticals » Vitamin B12 (Mecobalamin) CAS-no-13422-55-4
Dark Red solid MF: C63H90CoN13O14P MW: 1343.4
Synonyms: MECOBALAMINE;METHYLCOBALAMIN;cobalt-methylcobalamin;cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),;Methyl-5,6-dimethylbenzimidazolylcobalamin;
Product Categories: API;Pharmaceutical intermediates;PHARMACEUTICALS;Nutritional Supplements;Intermediates & Fine Chemicals;Vitamin B12;Nutrition Research;Vitamins;Vitamin Ingredients
| Melting point | >190°C (dec.) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Sparingly), Water (Slightly) |
| pka | pK1:7.64(+1) (25°C) |
| form | Solid |
| color | Dark Red |
| Odor | Odorless |
| biological source | synthetic (organic) |
| Water Solubility | Partially soluble in cold water, hot water. |
| Stability: | Light Sensitie |
| Assay | 98%-102% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Mecobalamin is used for peripheral nerve disorders treatment drug, compared with other vitamin B12 preparations, having good transfer on the nervous tissue, through the methyl transfer reaction, can promote nucleic acid, protein lipid metabolism, repairing the damaged nerve tissue. In homocysteine synthetic egg ammonia acid process, it plays a role of coenzyme, especially by deoxyuridine synthesis of thymidine, promoting DNA and RNA synthesis of participation. Also in the experiment of glial cells, the drugs can improve methionine synthase activity and promote the synthesis of myelin lipids lecithin. Improving the nerve tissue metabolism, can promot axis cable and protein synthesis, make the delivery rate of the skeletal protein close to normal, maintain axonal functions. Besides mecobalamin injections can inhibit nerve tissue of abnormal impulse conduction, promoting redl blood cells mature, split, improving anemia. Mecobalamin can be quickly restored due to lack of B12 and reduce the number of rat erythrocytes, hemoglobin, hematocrit value. Used for megaloblastic red blood cell anemia and peripheral nerve disorder due to the lack of vitamin B12.
1.It is used for the treatment of nervous system diseases, relieving pain and numbness, speeded relieving pain, improving pain caused by cervical spondylosis, treatment of sudden deafness, etc.
2.Methylcobalamin is a kind of endogenous coenzyme B12, participating in the one carbon unit cycle, playing an important role in the synthesis of methionine homocysteine methyl transfer reaction process.
CONTACT/Email address: Joy@coreychem.com
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