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Synonyms: Tris(3-hydroxypropyltriazolylMethyl)aMine ;THPTA;Tris(3-hydroxypropyltriazolylmethyl)amine;3,3′,3”-((4,4’4,”-nitrilotris(methylene))tris(1H-1,2,3-triazole-5,1-diyl))tris(propan-1-ol) -(THPTA);Tris(3-hydroxypropyltriazolylMethyl)a;
MF: C18H30N10O3 MW: 434.51
| Melting point | 331-336°C (decomposition) |
| Boiling point | 723.8±70.0 °C(Predicted) |
| density | 1.44±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Very Slightly) |
| purity | 97% |
| form | Solid |
| Appearance | White or light grey solid |
| Product manager | Joy Wu Email: Joy@coreychem.com |
–THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Acceleration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction. THPTA is a superior alternative to water-insoluble TBTA. a) J. Am. Chem. Soc. 2011, 133, 17993. b) Bioconjugate Chem. 2010, 21, 1912.
–Tris(3-hydroxypropyltriazolylmethyl)amine when complexed to copper(I) can be used as a catalyst.
CONTACT/Email address: Joy@coreychem.com
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