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Spermidine CAS-no-124-20-9

CAS NO.:124-20-9

Clear colourless liquid after melting            MF: C7H19N3                MW: 145.25 
Synonyms: 1,8-DIAMINO-4-AZAOCTANE;SPERMIDINE FREE BASE;SPERMIDINE;OMEGA-AMINOBUTYL-OMEGA-AMINOPROPYLAMINE;N1-(3-AMINOPROPYL)BUTANE-1,4-DIAMINE;N-(3-AMINOPROPYL)-1,4-BUTANDIAMINE;N-[3-AMINOPROPYL]-1,4-BUTANEDIAMINE;N-(3-AMINOPROPYL)-1,4-DIAMINOBUTANE

Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase.
 

Melting point  23-25 °C
Boiling point  128-130 °C (14 mmHg)
density  1.00 g/mL at 20 °C
refractive index  n20/D 1.479(lit.)
Fp  >230 °F
storage temp.  room temp
solubility  H2O: 1 M at 20 °C, clear, colorless
form  Liquid After Melting
Purity 99%
Specific Gravity 0.925
color  Clear colorless
PH 12.0-13.5 (25℃, 1M in H2O)
             Product manager                  Joy Wu;        Email: Joy@coreychem.com

Spermidine can be used in electroporation while transferring the DNA into the cell under the electrical impulse. May be used for purification of DNA-binding proteins. Spermidine is also used, along with calcium chloride, for precipitating DNA onto microprojectiles for bombardment with a gene gun.
Spermidine serves as a precursor of spermine and essential for both normal and neoplastic tissue growth. It was first detected in human sperm, but occurs widely in nature. It is essential in both normal and neoplastic tissue growth. Spermidine has a role in cell growth processes and the formation and interconversion of spermidine in mammalian cells has been reported. It has been studied in the regulation of tRNA methyltransferase activity and stimulates T4 polynucleotide kinase activity.

The biggest benefit of spermidine is its ability to reduce age-related diseases. It benefits cardioactive, spermidine can reduce the development of atherosclerosis in mice by reducing inflammation and improving cellular (mitochondria) function. It can reduce the formation of blood clots (platelet aggregation) and improve the normal dilation of cells lining blood vessels.

CONTACT/Email address: Joy@coreychem.com

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