Home » Products » Fine Chemicals » Spermidine CAS-no-124-20-9
Clear colourless liquid after melting MF: C7H19N3 MW: 145.25
Synonyms: 1,8-DIAMINO-4-AZAOCTANE;SPERMIDINE FREE BASE;SPERMIDINE;OMEGA-AMINOBUTYL-OMEGA-AMINOPROPYLAMINE;N1-(3-AMINOPROPYL)BUTANE-1,4-DIAMINE;N-(3-AMINOPROPYL)-1,4-BUTANDIAMINE;N-[3-AMINOPROPYL]-1,4-BUTANEDIAMINE;N-(3-AMINOPROPYL)-1,4-DIAMINOBUTANE
Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase.
| Melting point | 23-25 °C |
| Boiling point | 128-130 °C (14 mmHg) |
| density | 1.00 g/mL at 20 °C |
| refractive index | n20/D 1.479(lit.) |
| Fp | >230 °F |
| storage temp. | room temp |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | Liquid After Melting |
| Purity | 99% |
| Specific Gravity | 0.925 |
| color | Clear colorless |
| PH | 12.0-13.5 (25℃, 1M in H2O) |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Spermidine can be used in electroporation while transferring the DNA into the cell under the electrical impulse. May be used for purification of DNA-binding proteins. Spermidine is also used, along with calcium chloride, for precipitating DNA onto microprojectiles for bombardment with a gene gun.
Spermidine serves as a precursor of spermine and essential for both normal and neoplastic tissue growth. It was first detected in human sperm, but occurs widely in nature. It is essential in both normal and neoplastic tissue growth. Spermidine has a role in cell growth processes and the formation and interconversion of spermidine in mammalian cells has been reported. It has been studied in the regulation of tRNA methyltransferase activity and stimulates T4 polynucleotide kinase activity.
The biggest benefit of spermidine is its ability to reduce age-related diseases. It benefits cardioactive, spermidine can reduce the development of atherosclerosis in mice by reducing inflammation and improving cellular (mitochondria) function. It can reduce the formation of blood clots (platelet aggregation) and improve the normal dilation of cells lining blood vessels.
CONTACT/Email address: Joy@coreychem.com
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