(S)-3-Hydroxy Myristic Acid Methyl Ester

🔬Physical and chemical properties

Appearance: At room temperature, it is usually a white or off-white solid.
Melting point: The reported values in the literature vary slightly, mainly ranging from 34-35 °C to 43-45 °C.
Boiling point: Approximately 359.1 ± 15.0 °C (760 mmHg).
Density: Approximately 0.931 ± 0.06 g/cm³ (predicted value).
Solubility: Soluble in organic solvents such as DMSO, ethanol, and DMF; the solubility in water is relatively low.
Structural Characteristics:
The molecule contains a chiral center (the 3rd carbon is in the S configuration), which gives this compound special value in stereochemistry research.
LogP: Approximately 3.83 (indicating a relatively strong lipophilicity).
Hydrogen bond donor: 1; acceptor: 3.

📊Usage and Application

Synthesis of lipid A analogues: This compound is used to synthesize lipid A analogues containing glucose. These analogues have lipopolysaccharide (LPS) antagonistic activity and are utilized in immunological research to investigate the mechanism of action of endotoxins.
Biochemical research reagents: As a chiral model compound, they are used to study the modification process of fatty acids by enzymes, as well as the analysis of lipid behavior in chromatography/spectroscopy.
Organic synthesis intermediates: They can be used to synthesize more complex natural products or bioactive molecules.

🎯 Safety and Storage

Storage conditions:
Powder form: It is recommended to store in a sealed container at -20°C, with a shelf life of up to 3 years; it can be stored at 4°C for 2 years.
Solution state: It is recommended to store at -80°C for approximately 6 months; at -20°C for about 1 month. Repeated freezing and thawing should be avoided.
Transportation conditions: Short-distance transportation at normal temperature is usually stable.
Notes:

This product is for scientific research purposes only and should not be used on humans or for clinical treatment.
It is recommended to wear appropriate personal protective equipment (such as laboratory gloves and goggles) during the operation, and to conduct it in a fume hood.

📧 Contact Info:lucy@coreychem.com