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(R)-1-Boc-3-hydroxypyrrolidine-cas-no-109431-87-0

(R)-1-Boc-3-hydroxypyrrolidine

CAS NO.:109431-87-0

Purity : 99%
Appearance: White to off white solid powder

Product Name (R)-1-Boc-3-hydroxypyrrolidine
Synonyms BOC-(R)-3-HYDROXYPYRROLIDINE;(3R)-(-)-N-BOC-3-HYDROXYPYRROLIDINE;1-PYRROLIDINECARBOXYLICACID,3-HYDROXY-,1,1-DIMETHYLETHYLESTER,(3R)-;(R)-1-N-BOC-3-HhydroxypyrrolidiChemicalbookne;R-1-N-Boc-3-hydroxy-pyrroline;(3R)-3-Hydroxypyrrolidine,N-BOCprotected;(R)-(-)-N-BOC-3-pyrrolidinol,98%;3-(R)-Hydroxy-pyrrolidine-1-carboxylicacidtert-butylester
CAS NO 109431-87-0
Appearance White to off white solid powder
Purity 99%
MF C9H17NO3
MW 187.24
Contact selina@coreychem.com

(R)-1-Boc-3-hydroxypyrrolidine (CAS: 109431-87-0) is a chiral, Boc-protected pyrrolidine derivative commonly used in pharmaceutical synthesis and chiral intermediate preparation.

Key features:

  • The hydroxyl group at the 3-position of the pyrrolidine ring and a Boc-protected nitrogen atom help control reactivity and stereochemistry.

  • It serves as a chiral building block in the synthesis of a variety of biologically active compounds, including:

    • Antiviral and anticancer agents

    • Neuroactive molecules

    • Natural product analogues

  • It can also be used in asymmetric synthesis as a precursor to chiral ligands or auxiliaries.

The Boc group can be removed under acidic conditions (e.g., TFA), liberating the amine for further functionalization.

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