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PEP-K;PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT CAS-no-4265-07-0

CAS NO.:4265-07-0

White to off-white solid                              MF: C3H4KO6P                              MW: 206.13

Synonyms:  Phosphoenolpyruvic Acid Monopotassium Salt 〔PEP, Monopotassium Salt〕;2-(phosphonooxy)-2-propenoicacimonopotassiumsalt;Potassium 1-carboxyvinyl hydrogenphosphate;Phospho(enol)pyruvic acid MonopotassiuM salt 99%;PEP-K;PEP MONOPOTASSIUM SALT

Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase.

Melting point  175 °C (dec.)(lit.)
storage temp.  2-8°C
solubility  Methanol (Slightly), Water (Slightly)
form  solid
color  White to off-white
Water Solubility  Soluble in water. Slightly soluble in methanol.
Sensitive  Hygroscopic
Purity 99%
                Product manager                     Joy Wu;               Email: Joy@coreychem.com

Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.

Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.

Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase. One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis. In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.

CONTACT/Email address: Joy@coreychem.com

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