Nervonic acid

Nervonic acid (CAS: 506-37-6) is a long-chain monounsaturated fatty acid, chemically known as cis-15-tetracosenoic acid. It is mainly found in certain plant oils (such as Lunaria annua seed oil, camelina oil, and malania oleifera oil) and in the brain tissue of animals. Its main functions and applications include:

1. Nervous System Health and Repair

• Nervonic acid is an important component of the myelin sheath, which is essential for maintaining the structure and function of both the central and peripheral nervous systems.

• In some studies and nutritional formulations, it has been suggested to help repair damaged nerve fibers and promote nerve regeneration, with potential supportive effects in conditions such as multiple sclerosis and brain injury recovery.

2. Infant Brain Development

• During infant brain development, nervonic acid participates in the formation of the myelin sheath around nerve fibers, helping to enhance memory, learning ability, and neural response speed.

• Certain infant formula products or nutritional supplements include nervonic acid or oils rich in it.

3. Dietary Supplements and Functional Foods

• Used in functional foods and dietary supplements, especially in areas targeting cognitive improvement and delaying neurodegenerative diseases.

• Works synergistically with other unsaturated fatty acids such as DHA and EPA, and may have potential intervention effects on Alzheimer’s disease, Parkinson’s disease, and other conditions (still under research).

4. Research Use

• Used in biochemistry and neuroscience research to study lipid metabolism, neural development, and mechanisms of neurodegenerative diseases.

• Can serve as a reference material in lipidomics analysis (e.g., GC-MS, LC-MS).

⚠ Notes

• Nervonic acid is often found in natural oils in health products, while high-purity isolated nervonic acid is typically used for research or high-end nutritional applications.

• Should be stored in a cool, dark place to prevent oxidation of its unsaturated double bond.