N-(3-Hydroxyphenyl)-4-toluidine

🧪 1. Chemical Properties

• Molecular formula: C₁₃H₁₃NO

• Structure: The molecule contains both a hydroxyl group (–OH) and an amino group (–NH–), making it chemically reactive.

• Appearance: Light brown to gray solid, easily oxidized, and sensitive to light and air.

⚙️ 2. Main Functions and Applications

1️⃣ Intermediate for Antioxidants

• It serves as an important intermediate for the synthesis of various rubber antioxidants, such as 6PPD, 7PPD, and IPPD.

• Widely used in the rubber and tire industry to prevent rubber from aging, cracking, or degrading under heat, light, and ozone exposure.

2️⃣ Intermediate for Dyes

• Used in the production of azo dyes, sulfur dyes, and other color developers.

• The hydroxyl and amino groups facilitate diazotization reactions, producing dyes with good light and heat resistance.

3️⃣ Intermediate for Organic Synthesis

• Employed in fine chemical synthesis to prepare compounds containing hydroxy-aryl or amino-aryl structures.

• Can be used to synthesize pharmaceutical intermediates, pigments, and polymer additives.

🧬 3. Typical Downstream Products

⚠️ 4. Safety and Handling

• As an aromatic amine compound, it may be toxic or sensitizing.

• Proper protective equipment should be used to avoid skin contact and inhalation.

• Store in a cool, dry, and sealed environment, protected from light and oxidation.

✅ Summary

N-(3-Hydroxyphenyl)-4-toluidine mainly acts as an intermediate for rubber antioxidants, dyes, and fine chemicals.


It plays a crucial role in the production of 6PPD-type antidegradants, making it an important functional raw material in the rubber industry.