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methyl(R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate-cas-no-1454848-00-0

methyl(R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate

CAS NO.:1454848-00-0

Purity: 99%;

Boiling point: 452.5±45.0 °C(Predicted)

Density: 1.505±0.06 g/cm ³ (Predicted)

Acidity coefficient (pKa) : 5.63±0.10(Predicted)

 

Product Name methyl(R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate
Synonyms methyl(R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate;EOS-60622;Methyl2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate;Methyl2-{(1R)-1-[(2-amino-5-bromo-3-pyridinyl)oxy]ethyl}-4-fluorobenzoate;METHYL2-[(1R)-1-[(2-AMINO-5-BROMOPYRIDIN-3-YL)OXY]ETHYL]-4-FLUOROBENZOATE;Benzoicacid,2-[(1R)-1-[(2-amino-5-bromo-3-pyridinyl)oxy]ethyl]-4-fluoro-,methylester;(R)-2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoicacidmethylester;(R)-Methyl2-(1-((2-amino-5-bromopyridin-3-yl)oxy)ethyl)-4-fluorobenzoate
CAS NO 1454848-00-0
Purity 99%
MF C15H14BrFN2O3
MW 369.19
Contact selina@coreychem.com

Methyl (R)-2-(1-((2-amino-5-bromopyridin-3-yloxy)ethyl)-4-fluorophenyl)acetate (CAS: 1454848-00-0) is a complex fluorinated aromatic compound featuring key pharmacophoric groups, including:

  • Fluorinated phenyl ring (enhances lipophilicity and metabolic stability)

  • Aminopyridine moiety (common in kinase inhibitors and CNS-active drugs)

  • Bromo and amino substituents (reactive sites for further functionalization)

Main Applications:

  1. Pharmaceutical Intermediate:


    Serves as a building block in the synthesis of small-molecule drugs, potentially used in the development of kinase inhibitors, anti-inflammatory agents, or oncology-targeted therapies.

  2. Lead Compound Development:


    Used in SAR (Structure–Activity Relationship) studies for the optimization of drug candidates due to its rich functionalization and asymmetric center.

  3. R&D Building Block:


    Suitable for C–C, C–N, and amide bond formation in advanced pharmaceutical synthesis, especially in medicinal chemistry research and custom synthesis projects.

25KG/50KG/200KG per barrel; Or package according to customer needs

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