Methylboronic acid

Product Applications

1. Chiral Catalyst Synthesis (Core Application)

2. General Organic Synthesis Intermediate

1. Suzuki-Miyaura Cross-Coupling Reaction
    

   As a low-carbon alkyl boronic acid monomer, it participates in Suzuki coupling with aryl halides, heteroaryl halides and vinyl halides to introduce methyl groups onto aromatic rings and heterocyclic skeletons. It is indispensable for constructing methyl-substituted aromatics, drug molecular skeletons and OLED luminescent materials.

2. Boron-containing Building Block Preparation
    

   Used to synthesize various alkyl boronate esters, boroxines and other organoboron intermediates for subsequent functional group conversion, such as hydroxylation, amination and halogenation.

3. Pharmaceutical Intermediate Manufacturing

• Synthesis of small-molecule API intermediates: Introduce methyl substituents on heterocyclic cores of anti-inflammatory, anti-tumor and anti-diabetic drugs via coupling reactions.
• Preparation of boron-containing targeted drug fragments and boron neutron capture therapy (BNCT) precursor fragments.
• Production of chiral drug intermediates relying on CBS catalytic asymmetric reduction derived from methylboronic acid.

4. Electronic & Optoelectronic Materials

1. OLED / Organic Semiconductor Materials
    

   Serves as a boron monomer for synthesizing methyl-modified arylboronic acid intermediates, which are further coupled to prepare high-efficiency luminescent layers, hole-transporting and electron-transporting materials for OLED panels.

2. Organic Field-Effect Transistor (OFET) Raw Materials
    

   Modifies conjugated polymer backbones by methyl boronation to adjust molecular solubility and carrier transport performance.

5. Fine Chemical & Custom Synthesis Reagents

• Custom synthesis of specialty boronic acid derivatives for laboratories and fine chemical factories.
• Reagent for selective methyl functionalization in complex molecule total synthesis.
• Raw material for preparing boron-based flame retardant additives and organic boron surfactants.

6. Analytical Chemistry Auxiliary Reagent

Contact information:

Contact: Sophia Li

Email: sophia@coreychem.com