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White cyrstalline powder MF: C9H14N4O3 MW: 226.23
Synonyms: N-B-ALANYL-L-HISTIDINE;H-BETA-ALA-HIS-OH;L-IGNOTINE;L-BETA-ALANINE HISTIDINE;L-CARNOSINE;B-ALANYL-L-HISTIDINE;BETA-A-H;BETA-ALANYL-L-HISTIDINE
Product Categories: Food additive;amino;Amino Acids;chiral;Nutritional Supplements;API;Amino Acid Derivatives;cosmestic;APIs
L-Carnosine is a dipeptide composed of β-alanine and L-histidine that has been found in rat olfactory bulb, skeletal muscle, brain, kidney, and spleen tissues, as well as human skeletal muscle, and has diverse biological activities
| Melting point | 253 °C (dec.) (lit.) |
| alpha | 20.9 º (c=1.5, H2O) |
| Boiling point | 367.84°C (rough estimate) |
| density | 1.2673 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 21 ° (C=2, H2O) |
| storage temp. | -20°C |
| solubility | DMSO (Very Slightly), Water (Slightly) |
| Purity | 99% |
| form | crystalline |
| color | White |
| Optical Rotation | 20.9º(C=1.5,H2O) |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
L-Carnosine is a metal chelator that forms complexes with copper, cobalt, nickel, cadmium, or zinc. Dietary administration of L-carnosine (60 mg/kg per day) reduces plasma levels of advanced glycation end products (AGEs) in diabetic rats. It reduces brain edema, blood-brain barrier disruption, microglial activation, and neuronal apoptosis in a rat model of intracerebral hemorrhage when administered at a dose of 1,000 mg/kg. L-Carnosine reduces hepatic protein carbonylation and necrosis in a rat model of cirrhosis induced by bile duct ligation. It also reduces lung myeloperoxidase (MPO) activity, production of reactive oxygen species (ROS), and TNF-α and IL-6 levels, as well as alveolar hemorrhage, interstitial edema, and pulmonary leukocyte infiltration in a mouse model of LPS-induced lung injury.
L-Carnosine is a naturally-occurring histidine-containing compound and the biological role of this dipeptide is to act as cytosolic buffering agents. Other roles ascribed to L-Carnosine include action s as neurotransmitters, modulation of enzymic activities and chelation of heavy metals. Studies indicate an ability to boost the immunological functions. In cosmetics, it has anti-aging and skin-conditioning applications. L-Carnosine is a strong anti-glycosylation, free radical scavenging,anti-oxidant,anti-aging, anti-pollution.Brightenand repairthe skin. white powder.
CONTACT/Email address: Joy@coreychem.com
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