🌿✨Kryptofix 222 (CAS 23978-09-8) | Advanced Cryptand for Phase Transfer Catalysis, Radiochemistry & Metal Ion Complexation

Kryptofix 222 is a highly efficient cryptand and macrocyclic polyether compound widely used as a powerful metal ion complexing agent and phase transfer catalyst. Its unique three-dimensional cage structure enables strong coordination with alkali metal ions, particularly potassium ions, making it an indispensable reagent in advanced organic synthesis, radiopharmaceutical manufacturing, electrochemistry, and supramolecular chemistry research.

Due to its exceptional ion-binding capability, Kryptofix 222 can significantly enhance reaction efficiency, improve selectivity, and facilitate transformations that would otherwise be difficult under conventional conditions.

⭐ Key Features & Performance

• Strong and selective complexation of alkali metal cations
• Excellent phase transfer catalytic activity
• Enhances reactivity of ionic reagents in organic media
• Improves reaction rates and product yields
• Widely used in fluorination and isotope-labeling chemistry
• Suitable for high-value pharmaceutical and research applications
• Important tool in supramolecular and coordination chemistry

🏭 Chemical & Fine Chemical Applications

Kryptofix 222 is extensively utilized in organic synthesis as an efficient phase transfer catalyst. By complexing metal cations, it increases the nucleophilicity of counter anions and promotes numerous synthetic transformations.

Typical applications include:

• Nucleophilic substitution reactions
• Alkylation processes
• Fluorination chemistry
• Organometallic synthesis
• Specialty intermediate manufacturing
• Fine chemical production

Its ability to facilitate reactions under milder conditions makes it highly valuable for modern synthetic chemistry.

💊 Pharmaceutical & Radiopharmaceutical Applications

One of the most important applications of Kryptofix 222 is in radiopharmaceutical production, particularly in the synthesis of fluorine-18 labeled compounds used for positron emission tomography (PET).

Applications include:

• PET tracer synthesis
• Fluoride ion activation
• Radioisotope labeling
• Radiochemical research
• Pharmaceutical development

The compound plays a critical role in improving labeling efficiency and supporting the production of high-quality diagnostic imaging agents.

⚡ Electrochemistry & Advanced Materials Research

The exceptional ion-complexing properties of Kryptofix 222 make it valuable in electrochemical and materials science applications.

Researchers utilize the product for:

• Electrolyte system optimization
• Ion transport studies
• Functional material development
• Sensor technologies
• Energy storage research
• Advanced battery investigations

Its ability to control ion behavior contributes to the development of next-generation functional materials.

🧪 Supramolecular & Coordination Chemistry

Kryptofix 222 serves as a classic host molecule in supramolecular chemistry due to its cage-like structure and strong guest-binding properties.

Research applications include:

• Host-guest interaction studies
• Molecular recognition research
• Coordination chemistry
• Selective ion capture
• Academic and industrial R&D projects

These characteristics have made Kryptofix 222 a benchmark compound for studying molecular encapsulation and selective ion complexation.

📞 Contact Information

For samples, COA, pricing, or regulatory support, please contact:

Product Manager: Echo Liu

📧 Email: Echo@coreychem.com