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H-Gln(Trt)-OH-cas-no-102747-84-2

H-Gln(Trt)-OH

CAS NO.:102747-84-2

Purity : 99%
Appearance: White to off white solid powder

Product Name H-Gln(Trt)-OH
Synonyms H-GLN(TRT)-OH;L-GLUTAMINE (TRITYL);GLUTAMINE(TRT)-OH;N-GAMMA-TRITYL-L-GLUTAMINE;N-DELTA-TRITYL-L-GLUTAMINE;N-δ-Trityl-L-glutamine;H-Glu(Trt)-OH;H-L-Gln(Trt)-OH
CAS NO 102747-84-2
Appearance White to off white solid powder
Purity 99%
MF C24H24N2O3
MW 388.46
Contact selina@coreychem.com

H-Gln(Trt)-OH (CAS: 102747-84-2) is a side-chain protected form of L-glutamine, commonly used as a building block in solid-phase peptide synthesis (SPPS).

Key features:

  • The side-chain amide group is protected with a trityl (Trt) group, preventing unwanted side reactions such as deamidation or cyclization during peptide assembly.

  • The main-chain amino and carboxyl groups remain reactive, allowing for coupling in peptide chain elongation.

  • It is especially important in synthesizing peptides containing Gln residues, including therapeutic peptides, protein fragments, and vaccine components.

After synthesis, the Trt group can be cleaved under mildly acidic conditions (e.g., with TFA), restoring the native amide functionality of glutamine.

25KG/50KG/200KG per barrel;

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