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White powder; Purity 99% MF: C10H17N5NaO14P3 MW: 547.18
Synonyms: Guanosine 5′-triphosphate sodium salt hydrate;GUANOSINE-5′-TRIPHOSPHATE TETRASODIUM SALT;5′-triphosphate trisodium salt;GTP, trisodium salt, ≥96%(HPLC）;guanosine 5′-triphosphate sodium salt solution;Guanosine 5′-(tetrahydrogen triphosphate), trisodium salt;GUANOSINE 5′-TRIPHOSPHATE SODIUM 100 MM SOLUTION MO;
Guanosine 5′-triphosphate sodium salt solution has been used for reconstituting transducin during purification of transducin. GTP is usually supplied as the disodium salt in crystal form,and also be in solution form of 100mM Na and Tris.
| Melting point | 254 – 256°C |
| storage temp. | -20°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| color | white |
| biological source | Porcine brain ; bacterial (Corynebacterium); yeast |
| Optical Rotation | [α]20/D 24±2°, c = 1% in 0.5 M Na2HPO4 |
| Water Solubility | H2O: 50mg/mL |
| BRN | 4113439 |
| Stability: | Hygroscopic |
| Purity: | 99% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Guanosine 5′-triphosphate sodium salt solution has been used for reconstituting transducin during purification of transducin. GTP is supplied as the disodium salt in crystal form.
Biochem/physiol Actions :GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades.
Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
CONTACT/Email address: Joy@coreychem.com
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