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30618 84 9

Glyceryl monothioglycolate

CAS NO.:30618-84-9

Purity: 78% to 82%.
Appearance: Colorless transparent liquid.

Product Manager Email: Nicole@coreychem.com 

 

Product name Glyceryl monothioglycolate
Product Categories GLYCEROLMONOTHIOGLYCOLATE;Glycerol monomercaptoacetate;Mercaptoacetic acid monoester with 1,2,3-propanetriol;Acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol;
CAS NO. 30618-84-9
MF C5H10O4S
MW 166.2
Density  (at 20°C).
Structural formula 30618 84 9
Product Manager Email Nicole@coreychem.com

 

Frequently Asked Questions

Question 1: What is Glycerol Monomercaptoacetate?

Glyceryl monothioglycolate is an organic compound containing a sulfhydryl (-SH) group, with the chemical formula  . It is a colorless and transparent liquid, commonly used as a key active ingredient in personal care products (especially perms and hair straightening treatments). It is also known as glyceryl thioglycolate.
 
Question 2: What is the purity specification of this product?
Based on the provided technical data, the purity (assay) of this product typically ranges from 78% to 82%. Additionally, as an impurity control indicator, the content of free thioglycolic acid is strictly controlled to ≤2.0% to ensure the mildness and safety of the product.
 
Question 3: What are the physical properties of this product?
Appearance: Colorless transparent liquid.
Density: Approximately 1.315g/cm3(at 20°C).
Boiling Point: Approximately 244°C (at 101.325 Pa).
Solubility: Highly soluble in water, with water solubility reaching 1000g/L at 20°C.
pH Value: The pH of a 10% aqueous solution typically ranges from 2.0 to 3.5, making it acidic..
 
Question 4: Why choose Glycerol Monomercaptoacetate over standard thioglycolic acid in cosmetic formulations?
Compared to traditional ammonium thioglycolate or thioglycolic acid, Glycerol Monomercaptoacetate is less irritating to the skin and scalp and has a relatively milder odor. As a glycerol derivative, it also provides certain moisturizing properties, making it highly suitable for premium hair care products or those designed for sensitive scalps.
 
Question 5: What are the typical packaging specifications for this product?
Storage: For industrial or bulk purchases, it is usually packaged in 200L plastic drums, with a net weight of approximately 250kg per drum. Small-scale packaging (e.g., 100g reagent grade) is also available for laboratory R&D purposes.
 
 
 

Application 1 — Permanent Waving Lotions

This is the core application of the product. Acting as a reducing agent, it breaks the disulfide bonds in the hair, softening it and allowing it to be reshaped into curls. Due to its mild nature, it is widely used in “acid perms” or “cysteine perms” that cause less damage to the hair.

Application 2 — Hair Straightening Creams

In the hair straightening process, a reducing agent is also required to open the disulfide bond structure of the hair. Glycerol Monomercaptoacetate helps smooth out frizzy and curly hair, leaving it straight while better maintaining the hair’s natural shine compared to strong alkaline products.

Application 3 — Depilatory Creams

Utilizing its sulfhydryl (-SH) groups to disrupt the disulfide bonds in hair keratin, this product can also be used in depilatory creams to weaken the hair structure, making it easy to wipe off the skin surface. Its low-irritation characteristic makes it suitable for body care products.

Application 4 — pH Adjustment and Buffer Systems in Personal Care

Because its 10% aqueous solution is weakly acidic (pH 2.0-3.5), it not only serves as an active ingredient in formulations but also assists in adjusting the pH of the system to a weakly acidic range suitable for the scalp environment, thereby reducing the irritation of chemical treatments.

Application 5 — Organic Synthesis Intermediates

Beyond the personal care sector, as a compound containing both active sulfhydryl and hydroxyl groups, it serves as an important intermediate in organic synthesis. It can be used to synthesize other sulfur-containing compounds, polymer modifiers, or specific pharmaceutical intermediates (such as precursors for certain antibiotics or enzyme inhibitors).

 

Packaging:

1 L/bottle
30 L/plastic drum
200L/plastic drum
Other pack sizes available on request

Product actual photos:

Storage Conditions:

Store in a cool, dry, and well-ventilated area, away from direct sunlight, heat, and ignition sources.
Keep containers tightly sealed when not in use to prevent moisture absorption and contamination.
Store separately from strong oxidizing agents, strong bases, and combustible materials. Do not store together with food or feed.

For further information about the product, please contact:

Product Manager Email: Nicole@coreychem.com 

 

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