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Ginsenoside Rb1 CAS-no-41753-43-9

CAS NO.:41753-43-9

Synonyms: GINSENOSIDE GINSENOSIDE-RB1;GINSENOSIDE RB1;GINSENOSIDE RBL;(3beta,12beta)-20-[(6-o-beta-d-glucopyranosyl-beta-d-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside;2-O-beta-glucopyranosyl-(3beta,12beta)-20-[(6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl-beta-D-glucopyranoside; Ginsenoside Rb1  
 
MF: C54H92O23                      MW: 1109.29
 
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Isoprenoid/terpenoid;Biochemicals Found in Plants;Nutrition Research;ginsenoside series;Carbohydrates & Derivatives; Steroids;Saponins;The group of Ginsenosides

Melting point  197.5°C
Boiling point  766.35°C (rough estimate)
density  1.0971 (rough estimate)
refractive index  1.6500 (estimate)
storage temp.  2-8°C
solubility  methanol: soluble9.80 – 10.20 mg/mL, clear, colorless to faintly yellow
form  Solid
pka 12.85±0.70(Predicted)
color  Off-White to Pale Beige
biological source plant root (Panax ginseng)
Stability: Hygroscopic
Purity 98%
               Product manager                                   Joy Wu;               Email: Joy@coreychem.com

Ginsenoside Rb1, a glycosylated PPD type ginsenoside with two sugars linked to C-3 and two sugars linked to C-20, is the major active constituent of American ginseng. Studies have demonstrated the anti-aging effects of ginsenoside Rb1 at both animal and cell levels. 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD) is the major ingredient of ginsenoside Rb1, which has been shown to increase HAS2 expression by phosphorylating ERK and AKT signaling in human keratinocytes in a dose-dependent manner in vitro.
It is A major bioactive component of panax ginseng that promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. It has been reported to display immunostimulatory and anticancer effects. Reference standard in the analysis of herbal medicinal products.

CONTACT/Email address:  Joy@coreychem.com

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