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Light yellow powder MF: C15H10O5 MW: 270.24
Synonyms: 4H-1-Benzopyran-4-one,3,5,7-trihydroxy-2-phenyl;Galengin;3,5,7-Trihydroxy-2-phenyl-4h-benzopyran-4-one;Galangin Standard;Galangin, 98%, from Alpinia officinarum;3,5,7-Trihydroxy-2-phenyl-4H-chroMen-4-one; Galangin, >=98%
Product Categories: Antineoplastic;Flavanols;chemical reagent;pharmaceutical intermediate;phytochemical;
| Melting point | 214-215 °C(lit.) |
| Boiling point | 333.35°C (rough estimate) |
| density | 1.2319 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | room temp |
| solubility | Acetone (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 6.32±0.40(Predicted) |
| color | Light Yellow to Yellow |
| Purity | 98% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Galangin is a flavonoid naturally found in herbs used in traditional medicine. Like many flavonoids, it has potent antioxidant properties. It also has anti-inflammatory actions related to suppression of signaling through NF-κB in mice. Galangin acts as an antagonist of the aryl hydrocarbon receptor, inducing apoptosis in cancer cells. It also inhibits cytochrome P450 isoform 1A1 with an IC50 value of less than 1 μM.
Galangin is a flavanoid found in Alpinia officinarum, galangal rhizome (Alpinia galanga) and in propolis. Galangin has been show to inhibit proliferation of estrogen receptor-positive MCF-7 human breast cancer cells as well as delay of mammary tumorigenesis.It exhibits antioxidant, anti-apoptotic, anti-inflammatory and anti-obesity properties. In addition, it also possesses anti-genotoxic activity against environmental and dietary carcinogens. Galangin inhibits cancer growth by hindering cancer cell proliferation, induction of apoptosis and autophagy and inhibition of metastasis.
CONTACT/Email address: Joy@coreychem.com
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