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White to off-white solid MF: C30H50O MW: 426.72
Synonyms: FRIEDELAN-3-ONE;FRIEDELIN;DA-FRIEDOOLEANAN-3-ONE;FRIEDELIN, TECH.;FRIEDELIN hplc;FRIEDELIN WITH HPLC;DA-friedooleanan-3-one, Friedelan-3-one;D:A-Friedooleanan-3-one (van) (8ci)(9ci)
Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia?avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor?(H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent.
| Melting point | 262-265 °C (lit.) |
| alpha | D -27.8° (chloroform) |
| Boiling point | 477.2±13.0 °C(Predicted) |
| density | 0.963±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Purity | 98% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Friedelin is a flavonoid extract which displays radical scavenging and anti-typhoid activity.It is a pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork. It has a role as an anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and a plant metabolite. It is a pentacyclic triterpenoid and a cyclic terpene ketone.
Friedelin can be used as a starting material in the synthesis of:
CONTACT/Email address: Joy@coreychem.com
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