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folic acid cas no 59 30 3

Folic acid

CAS NO.:59-30-3

Assay: 95-102%

Appearance: Yellow or orange-yellow powder

Product Manager Email:jessie@coreychem.com

Product name Folic acid
Synonym EZNA KIT FUNGAL DNA MINI;KIT BLOOD DNA EZNA 5 TESTS;PTEROYL-L-GLUTAMIC ACID;PTEROYLMONOGLUTAMIC ACID;PTEROYLGLUTAMIC ACID;PTEROYGLUTAMIC ACID;PTEGLU
  59-30-3
Appearance Yellow or orange-yellow powder
Assay 95-102%
MF C19H19N7O6
MW 441.4
Related categories Multifunctional additive;Multifunctional raw material
Transport Information Not dangerous goods
Product photo
Product Manager Email: jessie@coreychem.com

 

Frequently Asked Questions

 

Question 1:What are the basic physical properties of Folic acid(CAS NO.: 59-30-3)?

Folic acid is a yellow to yellow-orange crystalline powder, practically odorless. Its molecular formula is C₁₉H₁₉N₇O₆, and its molecular weight is 441.40. It is very slightly soluble in water and insoluble in alcohol, acetone, and chloroform, but readily soluble in dilute solutions of alkali hydroxides and carbonates, forming soluble sodium folate salts. Folic acid is fairly stable in the solid state but is sensitive to heat and light, especially ultraviolet radiation. It should be stored in a well-closed, light-resistant container at room temperature.

Question 2:In terms of its application, what are the key features of this product?

Folic acid is a water-soluble B vitamin (Vitamin B9) that serves as a critical micronutrient for cellular one-carbon metabolism. Its most significant value lies in its role in preventing neural tube defects (NTDs) in newborns and treating megaloblastic anemia caused by folate deficiency. As a synthetic supplemental form of folate, it is widely used in food fortification (breads, cereals, flours) and pharmaceutical preparations. Key features include its essential role in DNA synthesis, cell division, and amino acid metabolism, as well as its ability to reduce homocysteine levels .

Question 3:What role does this product play in nutritional and therapeutic applications?

Folic acid is essential for nucleic acid (DNA and RNA) synthesis and amino acid interconversion. In therapeutic applications, it is the first-line treatment for folate-deficiency megaloblastic anemia. In preventive medicine, daily supplementation of 400 mcg is recommended for women of childbearing age to reduce the risk of neural tube defects such as spina bifida.

Question 4:How should this product be stored and handled?

Folic acid should be stored in a tightly closed, light-resistant container at controlled room temperature. It is sensitive to heat, light, and oxygen. Aqueous solutions are heat-sensitive and rapidly decompose in the presence of light and/or riboflavin, so solutions should be prepared fresh and protected from light. Contact with moisture can discolor or erode the product. Cooking and food processing can destroy 50-95% of folate content. It should be kept out of reach of children and used before the expiry date .

Question 5:How does the stability or formulation of this product affect its actual performance?

Folic acid is unstable under many conditions, particularly in solution. It degrades readily upon exposure to heat, UV light, and oxygen. Neutral solutions are relatively stable, but acidic solutions are less stable. The presence of riboflavin accelerates photodegradation. In food matrices, cooking, canning, and prolonged storage at ambient temperature can cause significant folate losses (up to 90% in some cases). Ascorbic acid and polyphenols may help limit degradation. For analytical or pharmaceutical applications, it is critical to protect folic acid from light and heat to maintain its bioactivity .

Application 1:What is the role of Folic Acid(CAS NO.: 59-30-3) in the Pharmaceutical Field?

Folic acid serves as a first-line therapeutic agent for megaloblastic anemia caused by folate deficiency. Its mechanism involves conversion to tetrahydrofolate (THFA), which functions as a coenzyme in one-carbon unit transfer, participating in nucleic acid and amino acid synthesis. When folate is deficient, DNA synthesis slows, leading to the formation of abnormally large and immature blood cells in the bone marrow—particularly red blood cells. Supplementation with folic acid provides therapeutic effects by promoting cell division and maturation.

Application 2:What is the role of Folic Acid in Preventive Medicine?

In the field of preventive medicine, folic acid plays a critical role in reducing the risk of neural tube defects (NTDs) in newborns. Women of childbearing age are recommended to supplement 400 mcg of folic acid daily to ensure adequate folate levels during early pregnancy, supporting normal neural tube development. 

Application 3:What is the role of Folic Acid in Food Fortification?

Folic acid is widely used as a nutritional fortifier in food processing. It is added to flour, cereals, breads, and various fortified foods to enhance their nutritional value. Due to folic acid’s instability during processing—losses can reach 50-95% during cooking and thermal treatment—various fortification techniques such as microencapsulation, fermentation, and genetic engineering are employed to improve its stability and bioavailability in food matrices.

Application 4:What is the role of Folic Acid in Animal Feed?

In the feed industry, folic acid serves as an essential vitamin additive for poultry and livestock. It promotes the formation of new cells and the maturation of red and white blood cells. Folic acid deficiency in chickens manifests as stunted growth, anemia, head and neck paralysis, and reduced egg production and hatchability. Supplementation at levels such as 50 mg per kilogram of feed effectively prevents and treats these deficiency symptoms.

Application 5:What is the role of Folic Acid in Cosmetics?

In cosmetic applications, folic acid functions as a skin-conditioning agent with moisturizing and anti-aging properties. It can bind up to 5,000 times its own weight in water, providing excellent hydration. Folic acid promotes DNA synthesis and cell metabolism, aiding in the repair of UV-induced skin damage and supporting the regeneration of skin cells. It is used in skincare formulations targeting photoaging and general signs of aging.

Conventional packaging:

1kg/bag;

25kg/drum;

According to customer needs

Storage Conditions:

Protected from light and preserved in well-closed containers.
The shelf ife is 36months from the date of production when stored in the unopened original container at room temperature.

For further information about the product, please contact:

Product Manager Email:jessie@coreychem.com

 

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