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White to off-white powder MF: C39H35NO4S MW: 613.76
Synonyms: FMOC-PEN(TRT)-OH;FMOC-PENICILLAMINE(TRT)-OH;FMOC-S-TRITYL-BETA,BETA-DIMETHYL-L-CYS-OH;FMOC-S-TRITYL-L-PENICILLAMINE;FMOC-CYSME 2(TRT)-OH;FMOC-L-PEN(TRT)-OH;FMOC-BETA,BETA-DIMETHYL-CYS(TRT)-OH;
| alpha | 33 º (c=1 in methanol) |
| Boiling point | 768.8±60.0 °C(Predicted) |
| density | 1.242±0.06 g/cm3(Predicted) |
| storage temp. | Store at -15°C to -25°C. |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 3.70±0.10(Predicted) |
| color | White to off-white |
| Optical Rotation | [α]/D +33±2°, c = 1 in methanol |
| Purity | 99% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation.
Fmoc-s-trityl-l-penicillamine is a new peptidomimetic furin inhibitors with potent anti-infectious activity.
CONTACT/Email address: Joy@coreychem.com
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