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Fmoc-Lys(pal-Glu-OtBu)-OH CAS-no-1491158-62-3

CAS NO.:1491158-62-3

White or off-white solid                     MF: C46H69N3O8                      MW: 792.06

Synonyms: Fmoc-Lys(Pal-Glu-OtBu)-OH;N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-gamma-glutamyl]-L-lysine 1′-(1,1-dimethylethyl) ester;(9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Pal-Glu-OtBu)-OH;N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(N-alpha’-palmitoyl-L-glutamic-acid alpha’-t-butyl ester)-L-lysine;(2S)-6-[(4S)-5-(tert-butoxy)-4-hexadecanamido-5-oxopentanamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid;L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-, 1′-(1,1-dimethylethyl) ester

Fmoc-Lys(Pal-Glu-OtBu)-OH is a racemic, solid-phase, industrial building block for the synthesis of peptides and polypeptides.

Boiling point  944.2±65.0 °C(Predicted)
density  1.099±0.06 g/cm3(Predicted)
storage temp.  Storage temp. 2-8°C
form  Solid
pka 3.88±0.21(Predicted)
color  White to off-white
Purity  99%
Product manager                   Joy Wu;                 Email: Joy@coreychem.com

Fmoc-Lys(Pal-Glu-OtBu)-OH can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Fmoc-Lys (Pal-Glu-OtBu)-OH is a non-cleavable antibody-drug conjugates linker capable of synthesizing antibody-drug conjugates. It can also be used as an alkyl chain-based PROTAC linker for the synthesis of PROTACs.
Fmoc-Lys(Pal-Glu-OtBu)-OH is a racemic, solid-phase, industrial building block for the synthesis of peptides and polypeptides. This product is used in the synthesis of liraglutide (a peptide), which is used to treat type 2 diabetes mellitus. It is synthesized by a solid phase process using coupling reactions with an acid labile linker. This product has been shown to be an efficient building block for the synthesis of peptides and polypeptides that have a sequence that can be varied by changing the protecting group on the amino acid.

CONTACT/Email address: Joy@coreychem.com

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