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DPPC;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE CAS-no-63-89-8

CAS NO.:63-89-8
White to Off-white solid                MF: C40H80NO8P               MW: 734.04
Synonyms: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE;1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE; LIPOID PE 180/180-PEG;L-A-LECITHIN DIPALMITOYL
Product Categories: Amines;Fatty Acid Derivatives & Lipids;Glycerols;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Other
DPPC, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine, is a phospholipid containing the 16 carbon fatty acid/palmitic acid (16:0) at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. Due to the medium size of fatty acid chain, DLPC is used to form thinner membranes or lipid bilayers.
Melting point  229-229.5 °C
alpha  D23 +6.6° (c = 4.2 in 1:1 chloroform-methanol)
storage temp.  -20°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
color  White to Off-White
biological source synthetic
Purity  98%
Stability: Stable. Incompatible with strong oxidizing agents.
 Product manager                                            Joy Wu;       Email: Joy@coreychem.com
  • 1,2-dipalmitoyl-sn-glycero-3-phosphocholine is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
  • 16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
  • 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
    1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

CONTACT/Email address: Joy@coreychem.com

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