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Red Solid MF: C29H38O4 MW: 450.61
Synonyms: TRIPTERIN;(2r,4as,6as,6ar,14as,14br)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid;3-HYDROXY-9BETA,13ALPHA-DIMETHYL-2-OXO-24,25,26-TRINOROLEANA-1(10),3,5,7-TETRAEN-29-OIC ACID ;Tripterine;24,25,26-Trinoroleana-1(10),
Product Categories: Chemical reagent;Proteasome Inhibitors;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Miscellaneous Natural Products;Pharmaceuticals;Steroids
Tripterine is a natural product with a variety of biological activity. It has a strong antioxidant effect, anti-cancer neovascularization effect as well as anti-rheumatoid effect.
| Melting point | 219-230°C |
| Boiling point | 645.7±55.0 °C(Predicted) |
| density | 1.2 |
| storage temp. | -20°C |
| solubility | DMSO: >10mg/mL |
| form | solid |
| pka | 4.78±0.70(Predicted) |
| color | red |
| λmax | 424nm(MeOH)(lit.) |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| Purity | 98% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Celastrol is an effective proteasome inhibitor. It has been confirmed that it is capable of inducing apoptosis of cancer cells through inhibiting proteasome activity.
Celastrol can be used as an antioxidant onstrated to have antiangiogenic activity, and be inhibitory against mice tumor growth by a few recent studies.
It is An antioxidant natural product Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Used for clinical treatment for rheumatoid arthritis, was demonstrated to have antiangiogenic activity.
Celastrol is an antioxidant natural product which inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Used for clinical treatment for rheumatoid arthritis, was demonstrated to have antiangiogenic activity, and be inhibitory against mice tumor growth by a few recent studies. Celastrol also has been shown to have the power to kill tumor cells and can work as an anticarcinogen. It is also a leptin sensitizer with the potential to reduce weight in obesity.
CONTACT/Email: Joy@coreychem.com
10G,100G,1kg,5kg in Aluminium foil Bag or Bottle;10kg,20kg,25kg in Fiber Can; Packing according to requirements.
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