C8-HSL

C8-HSL (N-Octanoyl-L-homoserine lactone, CAS: 147852-84-4) is a long-chain acyl homoserine lactone and functions as a quorum sensing (QS) signaling molecule in bacteria.

Main Functions and Applications

1. Quorum Sensing Signal Molecule

   • Produced and detected by Gram-negative bacteria (especially some Pseudomonas and Vibrio species) to regulate gene expression once the population reaches a certain threshold.

   • Regulates various biological processes such as virulence factor secretion, biofilm formation, and antibiotic production.

2. Microbiology and Pathogenesis Research

   • Used as a chemical probe to study bacterial communication and coordinated behaviors.

   • Helps elucidate the role of QS systems in the virulence mechanisms of pathogenic bacteria.

3. Development of Antimicrobial Strategies

   • Serves as a target molecule for the development of QS inhibitors aimed at designing novel anti-infective drugs by disrupting bacterial communication, thus reducing antibiotic resistance risks.

⚠️ Note:

C8-HSL is intended for research use only and is not for direct therapeutic or food additive applications.