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White powder;Purity 99% MF: C22H34N2O6 MW: 422.52
**Tirzepatide intermediate, Tirzepatide main chain
Synonyms: (S)-2-(3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanamido)-2-methylpropanoic acid;Boc-Tyr(tBu)-Aib-OH, Tirzepatide sidechain;Boc-Tyr(tBu)-Aib-OH;Boc-L-Tyr(tBu)-Aib-OH;Alanine, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-tyrosyl-2-methyl-;Tilpotide dipeptide
| Boiling point | 629.1±55.0 °C(Predicted) |
| density | 1.129±0.06 g/cm3(Predicted) |
| storage temp. | Store at room temperature, keep dry and cool |
| pka | 3.57±0.10(Predicted) |
| Appearance | White to off-white Solid |
| Optical Rotation | -2.5670°(C=1.0041g/100mL, DMF, 20°C, 589nm) |
| Safety info | Non DG |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It is a 39-amino-acid modified peptide with a C20 fatty diacid moiety that enables albumin binding and prolongs the half-life. Tirzepatide selectively binds to and activates both the GIP and GLP-1 receptors, the targets for native GIP and GLP-1.
Tirzepatide enhances first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose dependent manner.This Tirzepatide intermediate, CAS No. 2639221-78-4, is a main chain of Tirzepatide.
Abbreviated as Boc-Tyr(tBu)-Aib-OH, it is a di-peptide (P2), and the corresponding sequence on Tirzepatide is Peptide 1 to Peptide 2.
CONTACT/Email address: Joy@coreychem.com
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