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MF: C20H30N4O6S MW: 454.54
Synonyms: 6-[5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-4-YL)-PENTANOYLAMINO]-HEXANOIC ACID 3-HYDROPEROXYSULFONYL-2,5-DIOXO-PYRROLIDIN-1-YL ESTER SODIUM SALT;D-BIOTIN-AMIDOCAPROATE-N-HYDROXYSUCCINIMIDE ESTER;D-BIOTINOYL-EPSILON-AMINOCAPROIC ACID-N-HYDROXYSUCCINIMIDE ESTER;BIOTIN-X-NHS;BIOTIN-X-NHS, WATER-SOLUBLE;BIOTIN-X, SE
Product Categories: biotinyl;Labeling and Diagnostics Reagents;Cross Linking Reagents; BiotinylationReagents;Biotinylation Reagents;API intermediates;Biotin Derivatives
| Melting point | 169-171 °C |
| density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: ≤2 mg/mL with sonication |
| form | powder |
| pka | 13.90±0.40(Predicted) |
| color | White to Off-White |
| Appearance | white solid |
| Water Solubility | H2O: ≤2mg/mL (with sonication) DMF: 50mg/mL (Stable up to 2 months in dry DMF.) |
| Purity | 98% |
| Stability: | Moisture Sensitive |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
Biotin-LC-NHS Ester has an extended spacer arm which helps to minimize steric hindrance. The membrane permeability of this reagent allows it to be used for intracellular labeling. It can react efficiently with primary amino (-NH2) to form stable, irreversible amide bonds.Has been used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin solid surfaces, such as plastics, which may reduce antigenicity. It has also been used to enhance the detection of DNA on nitrocellulose.
A biotinylation reagent incorporating an aminocaproyl pacer? This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture.
Succinimidyl 6-(biotinamido)hexanoate is a biotinylation reagent incorporating an aminocaproyl “spacer”. This can reduce the steric hindrance in binding avidin to some biotinylated compounds when used to biotinylate both the antibody and the carrier in the Protein Avidin-Biotin Capture System. This system avoids the direct interaction of a captured antibody with solid surfaces, such as plastics, which may reduce antigenicity. It has also been used to enhance the detection of DNA on nitrocellulose. Has also been used as a cell surface labelling reagent.
CONTACT/Email address: Joy@coreychem.com
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