Benzoic acid, 4-[5-(trifluoromethyl)-1H-imidazol-2-yl]-, methyl ester

Benzoic acid, 4-[5-(trifluoromethyl)-1H-imidazol-2-yl]-, methyl ester (CAS: 2106447-92-9) is an aromatic carboxylic acid methyl ester containing a trifluoromethyl-substituted imidazole ring, commonly used as a pharmaceutical intermediate or synthetic building block.

Key characteristics:

• The imidazole ring is a privileged structure in drug discovery, often found in anti-inflammatory, antimicrobial, and anticancer agents.

• The trifluoromethyl (CF₃) group enhances lipophilicity, metabolic stability, and bioavailability.

• The methyl ester of benzoic acid allows for further chemical transformations.

Main applications:

• As an intermediate in the synthesis of bioactive molecules, particularly drugs targeting inflammation, infections, or neurological disorders.

• Useful in the development of novel drug candidates.

• Functions as a starting material for functionalization reactions in organic chemistry.