Benzamide, 3-hydroxy-N,N-dimethyl-4-nitro-

Benzamide, 3-hydroxy-N,N-dimethyl-4-nitro- (CAS: 1369878-15-8) is an important pharmaceutical intermediate, primarily used in the synthesis of Tigecycline, a broad-spectrum glycylcycline antibiotic.

This compound serves as a key building block in the multi-step synthesis of Tigecycline, contributing to the construction of its complex heterocyclic structure. Tigecycline is used for the treatment of complicated skin and intra-abdominal infections and is effective against multi-drug resistant pathogens such as MRSA and VRE.

Main applications include:

• Intermediate in Tigecycline synthesis

• Preparation of related impurities and analogs

• Medicinal chemistry and process development