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Purity: ≥98%
Appearance: White to orange to green powder crystals
Product Manager Email: Cherry@coreychem.com
| Product name | 8-Quinolinesulfonyl chloride |
| CAS NO. | 18704-37-5 |
| Appearance | White to orange to green powder crystals |
| Purity | ≥98% |
| MF | C9H6ClNO2S |
| MW | 227.67 |
| Related categories | Chemical Synthesis;Heterocyclic Building Blocks;Building Blocks |
| Transport Information | Not dangerous goods |
| HS Code | 2933490090 |
| Structural formula |  |
| Product Manager Email: | cherry@coreychem.com |
Frequently Asked Questions
8-Quinolinesulfonyl chloride is an aromatic sulfonyl chloride compound containing a quinoline ring and a sulfonyl chloride functional group. It is generally supplied as a solid and is sensitive to moisture because the sulfonyl chloride group can react with water.
The product should be stored in a cool, dry, dark, and tightly sealed environment. Avoid moisture and unnecessary exposure during handling.
8-Quinolinesulfonyl chloride can be prepared through established sulfonyl chloride chemistry, generally involving introduction and conversion of a sulfonyl functional group on the quinoline ring.
For commercial production, the main quality-control focuses are chemical identity, purity, moisture content, and batch consistency. HPLC, NMR, IR, and MS can be used for product characterization.
Its key feature is its role as a reactive sulfonylating intermediate.
The sulfonyl chloride group readily reacts with suitable nucleophiles, allowing the introduction of a quinoline-sulfonyl group into target molecules. This makes it useful in organic synthesis, medicinal chemistry, and specialty chemical research.
The main reactive site is the sulfonyl chloride (-SO₂Cl) group.
It can undergo substitution reactions with suitable nucleophilic compounds to form corresponding sulfonamides, sulfonates, and other sulfonyl derivatives. The quinoline ring provides an additional heteroaromatic structural component to the resulting molecule.
Because sulfonyl chlorides are moisture-sensitive, reactions and storage should be conducted under appropriately dry conditions.
8-Quinolinesulfonyl chloride should be handled as a moisture-sensitive organic intermediate.
Avoid contact with water or excessive humidity, and use appropriate gloves, eye protection, and ventilation during handling. Keep the original container tightly sealed when not in use.
Store in a cool, dry, dark, and well-ventilated environment, following the latest product SDS for detailed safety requirements.
Application 1: What is the role of 8-Quinolinesulfonyl chloride in organic synthesis?
8-Quinolinesulfonyl chloride is primarily used as a sulfonylating reagent and organic synthesis intermediate.
Its reactive sulfonyl chloride group enables the preparation of quinoline-containing sulfonyl derivatives for further chemical research and development.
Application 2: What is the role of 8-Quinolinesulfonyl chloride in medicinal chemistry?
It can be used as a building block for medicinal chemistry research.
The quinoline ring is an important heteroaromatic structural motif, while the sulfonyl chloride group provides a convenient functional handle for preparing structurally diverse sulfonamide derivatives.
Application 3: What is the role of 8-Quinolinesulfonyl chloride in pharmaceutical research?
8-Quinolinesulfonyl chloride can serve as a specialty intermediate in pharmaceutical and bioactive-molecule research.
It enables researchers to introduce a quinoline-sulfonyl structural unit into candidate molecules, supporting studies of molecular structure, biological activity, and structure-activity relationships.
Application 4: What is the role of 8-Quinolinesulfonyl chloride in heterocyclic chemistry?
The product combines a quinoline heterocyclic system with a reactive sulfonyl chloride group, making it useful for research involving functionalized heteroaromatic compounds.
It can support the development of quinoline-containing derivatives for organic and medicinal chemistry studies.
Application 5: What is the role of 8-Quinolinesulfonyl chloride in specialty chemical research?
8-Quinolinesulfonyl chloride can be used as a versatile research intermediate for developing functionalized sulfonyl compounds.
Its main value lies in the combination of a reactive sulfonyl chloride group and a quinoline framework, providing a convenient starting material for structural diversification.
Conventional packaging:
Product actual photos：
Storage Conditions:
Please store 8-Quinolinesulfonyl chloride (CAS NO.: 18704-37-5) in a cool, dry, dark, and well-ventilated environment.
Keep the container tightly sealed and protect the product from moisture, direct light, heat, and contamination.
For further information about the product, please contact:
Product Manager Email: Cherry@coreychem.com
