8-CHLORO-2-HYDROXYQUINOLINE

8-Chloro-2-hydroxyquinoline (CAS: 23981-25-1) is a multifunctional quinoline derivative featuring both a hydroxyl group at position 2 and a chlorine atom at position 8. The hydroxyl group enables strong chelation with metal ions, making this compound useful in the design of metal chelators, fluorescent probes, and biologically active complexes. The chloro substituent at position 8 allows for further derivatization via cross-coupling reactions, facilitating the synthesis of structurally diverse heterocycles. It is frequently employed as an intermediate in the development of pharmaceuticals, particularly antimicrobial, anticancer, and antimalarial agents. Additionally, its versatile structure makes it valuable in ligand design and medicinal chemistry optimization.