🔬 8-Anilino-1-naphthalenesulfonic Acid (CAS 82-76-8) | Fluorescent Probe & Biochemical Research Tool

🌟 Product Overview

8-Anilino-1-naphthalenesulfonic acid (ANS) is a widely used fluorescent probe reagent in biochemical and biophysical research. It is especially known for its ability to bind to hydrophobic protein regions, producing strong fluorescence signals, making it highly valuable in protein structure studies and binding analysis.

• 🧪 Chemical Name: 8-Anilino-1-naphthalenesulfonic acid
• 🌍 CAS No.: 82-76-8
• 🧬 Molecular Formula: C16H13NO3S
• ⚖️ Molecular Weight: 299.34
• 🎨 Appearance: Light yellow to brown powder

💡 1. Protein Folding & Structural Biology Research

ANS is best known for its use in protein conformational studies.

• 🧬 Detects hydrophobic regions of proteins
• 🔬 Used to study protein folding/unfolding processes
• ⚗️ Helps monitor structural changes under different conditions
• 📊 Common in biochemistry and molecular biology labs

👉 When proteins unfold, ANS fluorescence increases significantly ✨

🌈 2. Fluorescent Probe Applications

It acts as a sensitive environmental fluorescence indicator.

• 💡 Fluorescence increases in non-polar environments
• 🧪 Used to study protein-ligand interactions
• 🔍 Useful in membrane and binding site research
• 📈 Helps analyze molecular microenvironments

👉 A classic “signal reporter” in fluorescence studies 🌟

🧫 3. Enzyme & Biochemical Analysis

ANS is widely applied in enzymology and biochemical assays.

• 🧬 Monitoring enzyme conformational changes
• ⚗️ Studying protein-ligand binding dynamics
• 🧫 Used in diagnostic and analytical research
• 📊 Supports kinetic and structural experiments

👉 A key tool in understanding biomolecular behavior 🔬

🧪 4. Research & Laboratory Applications

It is mainly used in academic and industrial R&D environments.

• 🎓 University biochemical research
• 🧪 Pharmaceutical R&D studies
• 🔬 Protein chemistry experiments
• 📚 Molecular biology and biophysics research

👉 Essential reagent for advanced life science research 🌱

🌍 Summary

8-Anilino-1-naphthalenesulfonic acid (ANS) is a powerful fluorescent probe widely used in:

🔬 Protein folding studies

💡 Fluorescence-based analysis

🧬 Enzyme & binding research

🧫 Biochemical and pharmaceutical R&D