Home » Products » Pharmaceuticals » (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
| Specification | |
| Purity: | 98.0% |
| Supply | Kilograms, hunderd kilograms |
| Product Name: | (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester |
| Synonyms: | Posaconazole Impurity 53;((3S,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate;Posaconazole InterMediates;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-Methylphenyl)sulfonyl]oxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; |
| CAS: | 149809-43-8 |
| MF: | C21H21F2N3O4S |
| MW: | 449.47 |
| EINECS: | 1308068-626-2 |
| Melting point | 100-102°C |
| Boiling point | 608.1±65.0 °C(Predicted) |
| density | 1.4 |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | slightly sol. in Chloroform |
| pka | 2.75±0.10(Predicted) |
| Appearance | White to Orange to Green powder to crystal |
| Transport Information | non-hazardous goods |
| HS Code | 2933990099 |
| Uses | |
| Uses 1 | (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester is a pharmaceutical intermediate ingredient for Posaconazole is one of the newest triazole antifungal agents approved by the FDA for the prevention of invasive Aspergillus and Candida infections in immunocompromised patients. Such patients include haematopoietic stem cell transplant patients with graft-versus-host disease and patients with haematological malignancies undergoing chemotherapy. |
| Contact person: | Crystal@coreychem.com |
| Package: | Fluorinated bottle, fiber can |