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Cas no 149809 43 8 (5R cis) Toluene 4 sulfonic acid 5 (2,4 difluorophenyl) 5 (1H 1,2,4 triazol 1 yl)methyltetrahydrofuran 3 ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

CAS NO.:149809-43-8
Specification  
Purity: 98.0%
Supply Kilograms, hunderd kilograms
Product Name: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
Synonyms: Posaconazole Impurity 53;((3S,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)Methyl 4-Methylbenzenesulfonate;Posaconazole InterMediates;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-Methylphenyl)sulfonyl]oxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;
CAS: 149809-43-8
MF: C21H21F2N3O4S
MW: 449.47
EINECS: 1308068-626-2
Melting point 100-102°C
Boiling point 608.1±65.0 °C(Predicted)
density 1.4
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility slightly sol. in Chloroform
pka 2.75±0.10(Predicted)
Appearance White to Orange to Green powder to crystal
Transport Information non-hazardous goods
HS Code 2933990099
Uses  
Uses 1 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester is a pharmaceutical intermediate ingredient for Posaconazole is one of the newest triazole antifungal agents approved by the FDA for the prevention of invasive Aspergillus and Candida infections in immunocompromised patients. Such patients include haematopoietic stem cell transplant patients with graft-versus-host disease and patients with haematological malignancies undergoing chemotherapy.
Contact person: Crystal@coreychem.com
Package: Fluorinated bottle, fiber can
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