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5-CHLORO-2-NITROANISOLE CAS-no-6627-53-8

CAS NO.:6627-53-8

Light yellow powder; Purity 99%               MF: C7H6ClNO3               MW: 187.58

Synonyms: 4-chloro-2-methoxy-1-nitro-benzen;5-CHLORO-2-NITROANISOLE;4-CHLORO-2-METHOXYNITROBENZENE;4-chloro-2-methoxy-1-nitro-benzene;4-Chloro-3-methoxy-1-nitrobenzene;5-CHLORO-2-NITROANISOLE 

Melting point  70-72 °C(lit.)
Boiling point  289.1±20.0 °C(Predicted)
density  1.4219 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform, Ethyl Acetate
form  Solid
color  Yellow
Purity 99%
Safety info Non DG
            Product manager           Joy Wu;       Email: Joy@coreychem.com

5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs (1). In addition, it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells (2). It could be used for organic synthesis and pharmaceutical production.

CONTACT/Email address: Joy@coreychem.com

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