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Light yellow to off-white powder MF: C6H6N2O3 MW: 154.12
Synonyms: 5-ACETYL-1H-PYRAZOLE-3-CARBOXYLIC ACID; ODM-201 intermediate 1;1H-Pyrazole-3-carboxylic acid, 5-acetyl-;5-ACETYL-1H-PYRAZOLE-3-CARBOXYLIC ACID;5-Acetylpyrazole-3-carboxylic Acid;3-Acetyl-1H-pyrazole-5-carboxylic acid
| Melting point | 257-269 °C (decomp)(Solv: ethanol (64-17-5); benzene (71-43-2)) |
| Boiling point | 479.2±30.0 °C(Predicted) |
| density | 1.467±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 3.60±0.10(Predicted) |
| Appearance | Light yellow to off-white powder |
| Purity | 98% above |
| Product manager | Joy Wu; Joy@coreychem.com |
5-acetyl-1H-pyrazole-3-carboxylic acid can be used in the industrialization of substances such as polyurethanes. Impurities in this chemical are removed through filtration before it is used for synthesis.
5-Acetyl-1H-pyrazole-3-carboxylic acid can be considered a valuable building block for other types of organic and medicinal chemistry transformations and is the essential starting material for the preparation of Darolutamide, which is chemically known as N-{(2S)-1-[3-(3-chloro-4- cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl}-5-(1-hydroxyethyl)-1H-pyrazole-3- 10 carboxamide. It is an anti-androgen medication that is used for the treatment of prostate cancer in men. Recently, a safe and metal-free process using ethyl glycinate hydrochloride as the starting material has been developed to prepare 5-Acetyl-1H-Pyrazole-3-carboxylic acid[1-2].
CONTACT/ Email address: Joy@coreychem.com
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