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Appearance: off-white powder
Purity: 99%
| Product name | 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid |
| Synonym | 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoicacid(intermediateofpemetrexed);4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-1H-PYMOL[2,3-D]PYRIMODIN-5-YL)ETHYL]BENZOICACID;4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-BenzoicChemicalbookAcid;4-[2-（2-Amino-4-oxo-4,7-Dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-yl）ethyl]benzoicacid;Pemetrexedreferencesubstance;Benzoicacid,4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-(9CI);PemetrexedIntermediateBenzoicAcid;Pemetrexedacidintermediate |
| CAS No. | 137281-39-1 |
| Purity | 99% |
| MF | C15H14N4O3 |
| MW | 298.3 |
| Related categories | Pyrimidine; Pemicidetetra; Reference substance – Impurity reference substance; Pharmaceutical intermediate; Intermediate Organicacids; Pemetrexed series; Chemicals; Chemical intermediates; Biocatalysis; PEMETREXEDDISODIUM; (intermediateofpemetrexed); |
| Transport Information | Not dangerous goods |
| HS Code | 2933990099 |
| Structural formula | |
| Product Manager | Cara Lee Email: Cara@coreychem.com |
Frequently Asked Questions：
Question 1: What is the chemical name of CAS 137281-39-1?
A: The Chemical name is 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo [2,3-d] pyrimidin-5-yl) ethyl] benzoic Acid, short name Pemetrexed Acid.
Question 2:What is the appearance of Pemetrexed Acid?
A: The appearance of Pemetrexed Acid (CAS No.:137281-39-1) is Off-white powder.
Question 3: What is the typical purity specification of the product?
A: Typical purity ≥98% by HPLC; The purity we supply is ≥99%, total impurity is ≤1.0%.
Question 4:What is the content of related substances about CAS 137281-39-1?
A: The unspecified impurity is ≤0.2%,
Water is ≤6.5%
Resudie on ignition is ≤1.0%
Question 5: What is the recommended storage condition for Pemetrexed Acid?
A: Keep tightly sealed in a cool and dry place, away from oxidizing agents and protected from light.
Application 1: What is the core application of CAS 137281-39-1?
the core appication of 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid (CAS No.: CAS 137281-39-1) is as the key intermediate for the synthesis of anti-tumor API Pemetrexed disodium.
Application 2: What diseases can Pemetrexed disodium treat?
It is applied for the treatment of malignant pleural mesothelioma and non-small cell lung cancer.
Application 3：What applications does Pemetrexed Acid have in quality testing?
A: it can be used as a reference substance for pemetrexed-related impurities, employed for HPLC detection, quality research, and method validation in pharmaceutical enterprises.
Application 4：What new drug research directions can use this compound scaffold?
A: It belongs to pyrrolo [2,3-d] pyrimidine core, can be applied in synthesis and pharmacological activity screening of new antifolate anti-tumor lead compounds.
Application 5：Are there any other application scenarios?
A: It can be used as research reagent for CROs and research institutes to carry out in vitro cell and enzyme activity screening.
Conventional packaging:
1kg/bag
5kg/bag
25kg/drum
Storage Conditions:
Keep tightly sealed in a cool and dry place, away from oxidizing agents and protected from light.
★Our Superiority:
1. Factory direct supply, Competitive price in china market, long-term supply and adequate inventory.
2. Production Capacity: 500KG per month, also can adjust the production quantity according to the customer’s demand.
3. With stable quality and competitive price, Supplying this product to the markets of the United States, The south Korea and Europe etc for an extended period of time. And would like to supply free sample to our every customer.
4. Providing Certificate Of Analysis (COA), Material Safety Data Sheet (MSDS).
5. After-sale service: Timely after-service resolves your worry for international trade. If you have problem about the quality, we will arrange refunds in time.
❤ The customer would like to think, do the customers, to the customers:
Any interest, welcome to contact: cara@coreychem.com
