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Purity: ≥99%
Appearance: Colorless to light yellow liquid
Product Manager Email:ada@coreychem.com
| Product name | 2,5-Dimethyl-1H-pyrrole |
| Synonym | 2,5-1H-dimethylpyrrole;2,5-dimethyl-1h-pyrrol;2,5-dimethyl-pyrrol;Pyrrole, 2,5-dimethyl-;2,5-Dimethyl Pyrrole (625-84-3) |
| CAS NO. | 625-84-3 |
| Appearance | Colorless to light yellow liquid |
| Purity | ≥99% |
| MF | C6H9N |
| MW | 95.14 |
| Related categories | Food additives; Flavoring agents (aroma enhancers); Naturally identical and artificial flavors; Pyrrole; Heterocyclic building blocks; Organophosphorus ligands; General reagents; chemical raw materials |
| Transport Information | Not dangerous goods |
| HS Code | 2933990099 |
| Structural formula |  |
| Product Manager Email: | ada@coreychem.com |
Frequently Asked Questions
Q1:What are the main uses of 2,5-dimethylpyrrole?
2,5-dimethylpyrrole is an important chemical intermediate. It is mainly used as a building block for synthesizing pharmaceuticals and pesticides, and also has applications in the agricultural chemical industry. In addition, it is also used as a key pyrrole intermediate for the synthesis of macrocyclic compounds such as porphyrins and vitamin B12, as well as an intermediate for fragrances and dyes.
Q2:What are the physical characteristics of this product?
2,5-dimethylpyrrole typically appears as a colorless to light yellow liquid at room temperature, with an amine like odor. Its key physical parameters include a melting point of approximately 6.5-7.7 ° C, a boiling point of approximately 160-170 ° C (under different pressure conditions), and a density of approximately 0.96 g/mL.
Q3:What is the acute toxicity of 2,5-dimethylpyrrole?
According to toxicological data, this substance has moderate to high acute toxicity. The oral LD50 of rats is 59 mg/kg, and the dermal LD50 is 300 mg/kg. In the study of oral lethal dose, the observed effects include drowsiness, difficulty breathing, and diarrhea. It is classified as’ toxic by swallowing ‘,’ toxic by skin contact ‘, and’ toxic by inhalation ‘.
Q4:What personal protective measures should be taken during operation?
The operation should be carried out in a fume hood and avoid inhaling vapors or aerosols. Personal protective recommendations include wearing impermeable gloves (such as butyl rubber or fluororubber materials), safety goggles or face shields, and appropriate respiratory protective equipment. If clothing is contaminated, it should be replaced immediately.
Q5:What are the correct storage conditions?
It is recommended to store 2,5-dimethylpyrrole refrigerated (0-10 ° C) and store it under inert gas (such as nitrogen or argon) protection to avoid oxidation and polymerization. Containers should be kept sealed and stored in a dry, well ventilated area. This substance may change color when exposed to air, indicating oxidation.
1.What is the main use of 2,5-dimethylpyrrole in organic synthesis?
2,5-dimethylpyrrole is a universal building block mainly used for the synthesis of drugs and pesticides, and also has applications in the agrochemical industry. In addition, it is also used as a key pyrrole intermediate for the synthesis of macrocyclic compounds such as porphyrins and vitamin B12, as well as an intermediate for fragrances and dyes. Some suppliers also list it as an organic synthetic intermediate for the production of hexene-1 through ethylene polymerization.
2.What are the specific applications of this product in the field of materials science?
In materials science, 2,5-dimethylpyrrole has attracted attention due to its unique 2,5-position methyl blocking effect. Unsubstituted pyrrole is highly prone to oxidative polymerization at the alpha site, while the 2-position and 5-position of 2,5-dimethylpyrrole are blocked by methyl groups, making it inert to the polymerization process. This feature makes it suitable for:
1)Conductive polymer: Participate in the preparation of PPRV conductive polymer films.
2)Coordination chemistry: Formation of paramagnetic charge transfer complexes in 3D coordination polymers.
3)Corrosion inhibitor: As the backbone of N-aryl corrosion inhibitor, it exhibits corrosion inhibition effect under acidic conditions.
3.Can it be used in the field of spices or essence?
2,5-dimethylpyrrole is classified by the US FDA as a food flavoring or adjuvant, belonging to the category of “natural equivalent flavors and artificial flavors”. In the spice and essence industry, it can be used to mix specific odor characteristics to enhance the sensory experience of consumer goods.
4.What is the exploratory value of this compound in pharmaceutical research and development?
2,5-dimethylpyrrole has been explored in drug discovery, particularly in the creation of novel compounds with therapeutic potential, and therefore has received attention in medicinal chemistry research. Its positioning as a pharmaceutical intermediate also confirms its role as a building block in the synthesis route of active pharmaceutical ingredients (APIs).
5.Can this product be used for analytical testing or biological monitoring?
2,5-dimethylpyrrole can be used as an analytical derivative. Specifically, it can be used for biological monitoring of n-hexane exposure through a conversion reaction with 2,5-hexanedione. This indicates that it has certain analytical application value in the field of occupational health and exposure assessment.
Conventional packaging:
1kg/bottle;
5kg/bottle;
Packaging according to customer requirements.
Storage conditions:
1.Temperature requirements
It is recommended to store refrigerated at 0-10 ° C. For long-term storage of solid forms, it is recommended to store at -20 ° C for 3 years, but conventional liquid products are still stored at a standard temperature of 2-8 ° C.
2.Inert gas and light avoidance
This substance is prone to oxidation and discoloration in air, and should be stored under inert gas (such as argon) protection. At the same time, it should be stored in a cool and dry place away from light.
3.Containers and ventilation
The container should be kept sealed and stored in a well ventilated area. Avoid long-term contact with air to prevent quality degradation caused by oxidation and polymerization.
For quotes and more information, please contact:
Product Manager:ada@coreychem.com
