Home » Products » Pharmaceuticals » 2,3,4,6-Tetra-O-benzyl-D-glucopyranose CAS-no-4132-28-9
White crystalline powder MF: C34H36O6 MW: 540.65 Capacity: from hundreds of KGs to Tonnage
Product Categories: Halogenated Heterocycles ,Pyrazoles;Biochemistry;Glucose;O-Substituted Sugars;Sugars;aldehydes;Carbohydrates & Derivatives;Carbohydrate Synthesis;Monosaccharides;Specialty Synthesis;Carbohydrates;Carbohydrates A to;Carbohydrates P-ZBiochemicals and Reagents;Monosaccharide
2,3,4,6-Tetra-O-benzyl-D-glucopyranose is an important D-glucopyranose derivative, which is often used as a pharmaceutical intermediate in the synthesis of derivatives for the treatment of Alzheimer’s disease, diabetes, and cancer.
| Melting point | 145-149 °C(lit.) |
| Boiling point | 672.4±55.0 °C(Predicted) |
| density | 1.22±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Soluble in chloroform |
| pka | 11.87±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Optical Rotation | [α]20/D +49±2°, c = 2% in dioxane |
| Purity | 99% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
2,3,4,6-Tetra-O-benzyl-D-glucopyranose (cas# 4132-28-9) is a compound useful in organic synthesis. For example, it enables the preparation of α-glucopyranosyl chloride as well as 1-C-α-D-glucopyranosyl derivatives; it can also be used in the preparation of important D-glucopyranosyl derivatives for glucosylation and other reactions.
2,3,4,6-Tetra-O-benzyl-D-glucopyranose is an important D-glucopyranose derivative, which is often used as a pharmaceutical intermediate in the synthesis of derivatives for the treatment of Alzheimer’s disease, diabetes, and cancer. After activation with trifluoroacetic anhydride, 2,3,4,6-Tetra-O-benzyl-D-glucopyranose reacts with various silyl enol ethers or allyl silanes in the presence of Lewis acids to generate α-configured C-D-glucopyranosyl derivatives, and reacts with activated aromatic nucleophiles to generate the corresponding β-anomers[2]. It can also be used to synthesize the antibiotic (+)-nojirimycin.
CONTACT/Email address: Joy@coreychem.com
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