Home » Products » Pharmaceuticals » Pharmaceutical Intermediates » 2-Thioadenosine (Cangrelor intermediate 1) CAS-no-43157-50-2
Pale yellow solid; Purity 99% MF: C10H13N5O4S MW: 299.31
Synonyms: 2-Thioadenosine (Cangrelor intermediate 1);6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purine-2-thione;(2R,3R,4S,5R)-2-(6-aMino-2-Mercapto-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;Adenosine,1,2-dihydro-2-thioxo-;Cangrelor Impurity 6; 2,3-dihydro-2-thioxoAdenosine;
2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures.
| Melting point | >178°C (dec.) |
| Boiling point | 544.5±60.0 °C(Predicted) |
| density | 2.18±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 8.37±0.40(Predicted) |
| color | Pale Yellow to Yellow |
| Purity | 99% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures. In biology, it regulates the synthesis and degradation of important biomolecules such as DNA, RNA and proteins. It also regulates cell signalling pathways, including those involved in cell growth, proliferation and apoptosis. In addition, it plays a role in maintaining cellular redox balance and regulating oxidative stress.
2-Thioadenosine has application for developing platelet aggregation inhibitors.It is one Intermediate in the synthesis of cangrelor.
CONTECT/ Email address: Joy@coreychem.com
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