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2-Thioadenosine (Cangrelor intermediate 1) CAS-no-43157-50-2

CAS NO.:43157-50-2

Pale yellow solid; Purity 99%          MF: C10H13N5O4S                 MW: 299.31

Synonyms: 2-Thioadenosine (Cangrelor intermediate 1);6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purine-2-thione;(2R,3R,4S,5R)-2-(6-aMino-2-Mercapto-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol;Adenosine,1,2-dihydro-2-thioxo-;Cangrelor Impurity 6; 2,3-dihydro-2-thioxoAdenosine; 

2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures.

Melting point  >178°C (dec.)
Boiling point  544.5±60.0 °C(Predicted)
density  2.18±0.1 g/cm3(Predicted)
storage temp.  2-8°C(protect from light)
solubility  Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form  Solid
pka 8.37±0.40(Predicted)
color  Pale Yellow to Yellow
Purity  99%
             Product manager  Joy Wu; Email: Joy@coreychem.com

2-Thioadenosine is a pharmaceutical intermediate compound used in the preparation of cangrelor, a P2Y12 platelet receptor antagonist used to prevent or reduce the risk of thrombosis during stenting procedures. In biology, it regulates the synthesis and degradation of important biomolecules such as DNA, RNA and proteins. It also regulates cell signalling pathways, including those involved in cell growth, proliferation and apoptosis. In addition, it plays a role in maintaining cellular redox balance and regulating oxidative stress.
 2-Thioadenosine has application for developing platelet aggregation inhibitors.It is one Intermediate in the synthesis of cangrelor.

CONTECT/ Email address: Joy@coreychem.com

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