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2′-O-Methyladenosine CAS-no-2140-79-6

CAS NO.:2140-79-6

White ot off white powder                       MF: C11H15N5O4                        MW: 281.27

Synonyms: 2′-OMe-rA;2′-O-Methyladenosine, 99.0%;2′-O-Me-Ado;-O-Methyladenosine;2-Amino-N6-(dimethylaminomethylidene)-N2-isobutyryl-2’AMI;2′-O-Methyladdenosine; 
 
Product Categories: Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides; Heterocycles;Nucleotides;Nucleosides;Nucleosides-2′-OMe Nucleosides

Melting point  200-202 C
Boiling point  623.8±65.0 °C(Predicted)
density  1.84±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Water (Slightly)
form  Powder
pka 13.13±0.70(Predicted)
color  White to Off-white
Optical Rotation -50.5°(C=0.01 g/mL H2O)
Water Solubility  Soluble in water.
Purity 99%
          Product manager                    Joy Wu;          Email:Joy@coreychem.com

2′-O-Methyladenosine (Cordysinin B) is a member of the class of adenosines that is adenosine in which the hydroxy group at position 2′ is replaced by a methoxy group. It has been isolated from the mycelia of Cordyceps sinensis. It has a role as a fungal metabolite. It is a member of adenosines and an ether. It derives from an adenosine. analogue with antiviral properties, starting material for 2′-O’-methyl nucleotides. Potential metabolite of 2′-O-Me-cAMP.

2′-O-Methyladenosine is an analog of adenosine used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase. Adenosine analog.  2′-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2′-O-Methyladenosine exhibits unique hypotensive activities.

CONTACT/Email address: Joy@coreychem.com

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