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Off-white to light yellow powder MF: C8H8N2OS MW: 180.23
Synonyms: 5-Methoxye-2-mercaplobenzinidazole;TIMTEC-BB SBB000219;5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;5-Methoxybenzimidazole-2-thiol;5-METHOXY-2-THIOBENZIMIDAZOLE;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-METHOXY-2-BENZIMIDAZOLETHIOL;2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE
Product Categories: pharm chemical,electronic;Aromatics; BENZIMIDAZOLE;Benzimidazoles;Building Blocks;Heterocyclic Building Blocks;BUILDING BLOCKS;Imidazol&Benzimidazole;(intermediate of omeprazole);
| Melting point | 261-263 °C(lit.) |
| Boiling point | 309.4±44.0 °C(Predicted) |
| density | 1.2425 (rough estimate) |
| vapor pressure | 0.001Pa at 25℃ |
| refractive index | 1.5690 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Sparingly) |
| form | Powder |
| pka | 10.13±0.30(Predicted) |
| color | Off-white to light yellow-brown |
| Water Solubility | insoluble |
| Sensitive | Air Sensitive |
| Purity | 99% |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.
CONTACT/Email address: Joy@coreychem.com
1kg,5kg in aluminium foil Bag or bottle;10kg,20kg,25kg in Fiber Can; Packing according to requirements.
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