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Appearance: Clear colorless to pale‑yellow liquid
Purity: 97%
| Product name | 2-Furaldehyde diethyl acetal |
| Synonym | 2-(diethoxymethyl)-fura;Furan,2-(diethoxymethyl)-;2-FURALDEHYDEDIETHYLACETAL;2-FURALDEHYDEDIETHYLACETAL;1-[(2R,4S,5S)-4-azido-5-(hyChemicalbookdroxymethyl)-2-thiolanyl]-5-methylpyrimidine-2,4-dione;2-(diethoxymethyl)furane;furfuraldiethylacetal;2-Furaldehydediethylacetal |
| CAS No. | 13529-27-6 |
| Purity | 97% |
| MF | C9H14O3 |
| MW | 170.21 |
| Related categories | Furan&Benzofuran;Building Blocks;Furans;Heterocyclic Building Blocks |
| Transport Information | Not dangerous goods |
| HS Code | 2932190090 |
| Structural formula | |
| Product Manager | Cara Lee Email: Cara@coreychem.com |
Frequently Asked Questions：
Question 1: What are its key physicochemical properties, appearance & odour of 2-Furaldehyde diethyl acetal?
A: 2-Furaldehyde diethyl acetal is pale-yellow clear liquid with faint nut-like odour; the flashing point is 64℃, insoluble in water, soluble in organic solvents.
Question 2: What handling precautions are required when using 2-Furaldehyde diethyl acetal?
A: 2-Furaldehyde diethyl acetal undergoes hydrolysis in strong acid to produce furfural and ethanol. Avoid using strong acids and strong oxidants; the operation should be carried out in a fume hood, and protective equipment should be worn, keeping away from heat sources.
Question 3: Based on its acid‑de‑protectable acetal structure, what are its main applications??
A: 2-Furaldehyde diethyl acetal is a furan-based synthetic building block used for multi-step heterocyclic synthesis. It can be sued as pharmaceutical intermediates, intermediate for the synthesis of fragrances and a substrate for heterocyclic chemical research.
Question 4:What are transportation requirements for this non‑hazardous combustible liquid? How to deal with spillage and human contact??
A: During transporatation, use sealed HDPE/carbon steel containers and keep away from high temperatures, strong acids and oxidants.
For minor leaks, inert substances can be used for absorption; do not discharge into sewers. After skin or eye contact, immediately rinse with plenty of flowing water; those who inhale should be moved to an area with fresh air.
Question 5: Is 2‑furaldehyde diethyl acetal (CAS:13529‑27‑6) classified as hazardous chemical?
A: 2‑furaldehyde diethyl acetal is a common flammable chemical and is not classified as a hazardous material for transportation.
Application 1: What practical problem can 2‑furaldehyde diethyl acetal solve in multi‑step functionalization of furan rings? Please give one typical case?
Furfural’s aldehyde group easily oxidizes or polymerizes in reactions. The acetal structure shields it under neutral or weakly‑alkaline conditions to avoid side reactions. Once furan‑ring modification completes, dilute acid restores the aldehyde group. For example, direct nitration destroys furfural’s aldehyde group; this product protects it to keep the group intact during nitration.
Application 2: What is its specific function in Pd‑mediated cross‑coupling, and what downstream molecules can be obtained?
A: It serves as stable furan‑containing substrate for Suzuki / Heck C‑C coupling. Acetal remains intact during reaction; aldehyde is regenerated by acidic post‑treatment. It reacts with aryl‑ or pyridyl halides to yield 5‑aryl‑2‑furaldehyde and 5‑pyridyl‑2‑furaldehyde heterocyclic intermediates for early‑stage drug screening (lab‑scale only, not for commercial API).
Application 3: What is its real positioning in flavor‑fragrance industry instead of direct perfume ingredient? What are application scenarios?
A: 2‑furaldehyde diethyl acetal is used as synthetic precursor, not as final flavor additive. Its acetal structure delivers better stability than free furfural under alkaline conditions. It is used to synthesize nutty, roasted, coffee‑type furan derivatives for baked‑food flavors and soap‑based daily‑use fragrances, reducing oxidation discoloration.
Application 4：What research‑oriented applications does it have for biomass‑derived fine chemicals?
A: Derived from biomass‑based furfural, it is used in lab process development. It undergoes acid‑catalyzed acetal exchange with other alcohols to produce furfural acetal derivatives screened as potential fuel oxygenate candidates. It also acts as model substrate to evaluate activity of solid‑acid catalysts at lab scale, not mass‑produced industrially.
Application 5：What is its application boundary in pharmaceutical field?
A: It is strictly a lab‑scale building‑block for lead‑compound optimization, NOT an API drug substance. In CRO and academic labs, it protects aldehyde during fragment assembly and cyclization. After molecular construction, acidic deprotection affords furan‑containing lead intermediates for in‑vitro bioassay only, not for pharmaceutical formulation.
Conventional packaging:
1kg/bottle
5kg/bottle
25kg/drum
Storage Conditions:
Store in tightly closed container. Keep in cool, dry and well‑ventilated place. Keep away from strong acids, oxidants and heat sources.
★Our Superiority:
1. Factory direct supply, Competitive price in china market, long-term supply and adequate inventory.
2. Production Capacity: 500KG per month, also can adjust the production quantity according to the customer’s demand.
3. With stable quality and competitive price, Supplying this product to the markets of the United States, The south Korea and Europe etc for an extended period of time. And would like to supply free sample to our every customer.
4. Providing Certificate Of Analysis (COA), Material Safety Data Sheet (MSDS).
5. After-sale service: Timely after-service resolves your worry for international trade. If you have problem about the quality, we will arrange refunds in time.
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