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2-Fluoroadenine CAS-no-700-49-2

CAS NO.:700-49-2

White to light yellow solid              MF: C5H4FN5             MW: 153.12
Product Categories: Biochemistry;Nucleobases and their analogs;Purine;Chemical Amines;Purines;Nucleosides, Nucleotides & Related Reagents;

2-Fluoroadenine is a purine nucleoside analog which has been investigated for suicide gene therapy for human malignancy.

Melting point  >350 °C(lit.)
Boiling point  239.6±50.0 °C(Predicted)
density  2.05±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  DMSO (Sparingly, Sonicated, Heated), Methanol (Slightly, Heated)
form  Solid
pka 6.84±0.20(Predicted)
color  White to Light Yellow
Purity  99%
       Product manager        Joy Wu;     Email: Joy@coreychem.com

2-Fluoroadenine is a fluorinated heterocyclic 2-ring compound. It is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. 2-Fluoroadenine has been used as an intermediate for antineoplastic drugs such as fludarabine. fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia.

It is a purine nucleoside phosphorylase gene therapy for human malignancy.It has been used in the synthesis of heat shock protein 90 (Hsp90) inhibitors that have anticancer activity in vitro. 

CONTACT/Email address: Joy@coreychem.com

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