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White to slightly yellow powder MF: C5H10O4 MW: 134.13
Synonyms: D-.alpha.-Ribodesose;Deoxyribose;D-Ribose, 2-deoxy-;2-deoxy-d-erythro-pentos;2-Deoxypentose;2-Desoxy ribosoe;D-(-)-2-DEOXYRIBOSE;D-2-DEOXYRIBOSE
Product Categories: FINE Chemical & INTERMEDIATES;Pharmaceutical Raw Materials;Riboses and 2′-Deoxyriboses;Biochemistry;Deoxysugars;Nucleosides, Nucleotides & Related Reagents;Ribose;Sugars;
2-deoxy-D-Ribose is a reducing sugar formed as a degradation product during metabolism of thymidine by thymidine phosphorylase.
| Melting point | 89-90 °C(lit.) |
| alpha | -57 º (c=1, H2O, 24hr) |
| Boiling point | 167.23°C (rough estimate) |
| density | 1.0590 (rough estimate) |
| refractive index | -56 ° (C=1, H2O) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Crystalline Powder |
| Purity | 99% |
| color | White to slightly yellow |
| Optical Rotation | [α]22/D 59°, c = 1 in H2O |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| Safety info | Non DG |
| Product manager | Joy Wu; Email: Joy@coreychem.com |
2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.
2-Deoxy-D-ribose (2dDR) can be used to prepare multifunctional wound dressings capable of inducing rapid angiogenesis with antimicrobial activity, such as 2dDR-SA hydrogel. The gel can be used to stimulate wound healing and treat superficial skin wounds, including chronic wound care. In addition, 2dDR gel has the potential to treat androgenetic alopecia and other causes of alopecia areata.
Hair Regrowth in Mice: Applying a small dose of 2-deoxy-D-ribose to mice models led to significant hair regrowth.
Blood Vessel Formation: The hair regrowth was linked to forming new blood vessels, enhancing blood supply to hair follicles.
Comparable to Minoxidil: The effectiveness of 2-deoxy-D-ribose in regrowing hair was similar to that of Minoxidil, a widely used hair loss treatment.
CONTACT/Email address: Joy@coreychem.com
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