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2 Deoxy 2 fluoro L fucose cas no 70763 62 1

2-Deoxy-2-fluoro-L-fucose

CAS NO.:70763-62-1

Appearance:White to off-white solid

Purity:99% Min

Product name 2-Deoxy-2-fluoro-L-fucose
Synonym (3S,4R,5S,6S)-3-Fluoro-6-methyl-tetrahydropyran-2,4,5-triol;
L-Galactose,2,6-dideoxy-2-fluoro-;
2,6-dideoxy-2-fluoro-L-Galactose;
(2S,3R,4R,5S)-2-Fluoro-3,4,5-trihydroxyhexanal;
2-fluorofucose
CAS NO. 70763-62-1
Appearance White to off-white solid
Purity 99% Min
MF C6H11FO4
MW 166.15
Structural formula
Related categories Pharm intermediate
Transport Information Non-hazardous goods
HS Code 2940000080
Product Manager Email sophia@coreychem.com

2-Deoxy-2-fluoro-L-fucose (CAS 70763-62-1) – Product Introduction

 
Core Identity

 

2-Deoxy-2-fluoro-L-fucose is a synthetic analog of L-fucose and is widely recognized as a specific and potent inhibitor of fucosylation. It functions by blocking the de novo synthesis of GDP-fucose in mammalian cells, thereby inhibiting the fucosylation of cell surface glycoproteins and glycolipids.

 
Key Applications
 
  1. Cancer Research & Anti-Cancer Drug Development
     
    • Target Validation: Fucosylation is a well-established biomarker linked to the progression, invasion, and metastasis of many cancers, including pancreatic cancer and hepatocellular carcinoma. This compound serves as a critical tool to study the role of fucosylation in tumorigenesis.
    • Drug Discovery: It is used to screen and develop potential anti-cancer therapeutics that target abnormal fucosylation pathways.
     
  2. Functional Glycobiology & Basic Science
     
    • Mechanism Study: A key reagent for elucidating the biological functions of fucosylation in cell adhesion, signal transduction, and cell differentiation.
    • Disease Modeling: Utilized to create cellular models of glycosylation disorders to understand the link between abnormal fucosylation and disease states.
     
  3. Inflammation & Immunology Research
     
    • Helps investigate the role of fucosylation in immune cell activation and inflammatory responses, providing insights for treating autoimmune diseases.
     
  4. Organic Synthesis & Intermediates
     
    • Serves as a valuable synthetic building block due to its unique fluorinated sugar structure, used in the synthesis of specialized pharmaceuticals, fine chemicals, and agrochemicals.
     
  5. Laboratory Reference Standards
     
    • Widely used as a certified reference material for analytical techniques such as HPLC and MS, ensuring accuracy in scientific testing and analysis.
     
 
Business Focus

 

We are pleased to offer high-purity 2-Deoxy-2-fluoro-L-fucose, meticulously produced to meet the rigorous standards of scientific research and industrial development. Our dedicated team provides comprehensive technical support, including custom synthesis and technical documentation, to ensure your project success.

 
 
 
 

Contact information:

Contact: Sophia Li

Email: sophia@coreychem.com

Packaging is done according to product characteristics and customer requirements.

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